Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes

被引：0

作者：

Brett T Staahl

Madhurima Benekareddy

Claire Coulon-Bainier

Ashwin A Banfal

Stephen N Floor

Jennifer K Sabo

Cole Urnes

Gabriela Acevedo Munares

Anirvan Ghosh

Jennifer A Doudna

机构：

[1] University of California,Department of Molecular and Cell Biology

[2] Roche Pharma Research and Early Development,MBIB Division

[3] E-Scape Bio,Department of Chemistry

[4] Howard Hughes Medical Institute,undefined

[5] University of California,undefined

[6] Innovative Genomics Institute,undefined

[7] University of California,undefined

[8] Lawrence Berkeley National Laboratory,undefined

[9] University of California,undefined

来源：

Nature Biotechnology | 2017年 / 35卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Gene editing in the mouse brain is achieved by injection of Cas9 ribonucleoprotein complexes.

引用

页码：431 / 434

页数：3

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