Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes

被引：0
|
作者：
Brett T Staahl
Madhurima Benekareddy
Claire Coulon-Bainier
Ashwin A Banfal
Stephen N Floor
Jennifer K Sabo
Cole Urnes
Gabriela Acevedo Munares
Anirvan Ghosh
Jennifer A Doudna
机构：
[1] University of California,Department of Molecular and Cell Biology
[2] Roche Pharma Research and Early Development,MBIB Division
[3] E-Scape Bio,Department of Chemistry
[4] Howard Hughes Medical Institute,undefined
[5] University of California,undefined
[6] Innovative Genomics Institute,undefined
[7] University of California,undefined
[8] Lawrence Berkeley National Laboratory,undefined
[9] University of California,undefined
来源：
Nature Biotechnology | 2017年 / 35卷
关键词：
D O I：
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学科分类号：
摘要：
Gene editing in the mouse brain is achieved by injection of Cas9 ribonucleoprotein complexes.
引用
收藏
页码：431 / 434
页数：3
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