Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes

被引：0
|
作者：
Brett T Staahl
Madhurima Benekareddy
Claire Coulon-Bainier
Ashwin A Banfal
Stephen N Floor
Jennifer K Sabo
Cole Urnes
Gabriela Acevedo Munares
Anirvan Ghosh
Jennifer A Doudna
机构：
[1] University of California,Department of Molecular and Cell Biology
[2] Roche Pharma Research and Early Development,MBIB Division
[3] E-Scape Bio,Department of Chemistry
[4] Howard Hughes Medical Institute,undefined
[5] University of California,undefined
[6] Innovative Genomics Institute,undefined
[7] University of California,undefined
[8] Lawrence Berkeley National Laboratory,undefined
[9] University of California,undefined
来源：
Nature Biotechnology | 2017年 / 35卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Gene editing in the mouse brain is achieved by injection of Cas9 ribonucleoprotein complexes.
引用
收藏
页码：431 / 434
页数：3
相关论文
共 50 条
  • [21] Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
    Farboud, Behnom
    Jarvis, Erin
    Roth, Theodore L.
    Shin, Jiying
    Corn, Jacob E.
    Marson, Alexander
    Meyer, Barbara J.
    Patel, Nipam H.
    Hochstrasser, Megan L.
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2018, (135):
  • [22] Nanoparticle Delivery of CRISPR/Cas9 for Genome Editing
    Duan, Li
    Ouyang, Kan
    Xu, Xiao
    Xu, Limei
    Wen, Caining
    Zhou, Xiaoying
    Qin, Zhuan
    Xu, Zhiyi
    Sun, Wei
    Liang, Yujie
    FRONTIERS IN GENETICS, 2021, 12
  • [23] Delivery of CRISPR/Cas9 for therapeutic genome editing
    Xu, Xiaojie
    Wan, Tao
    Xin, Huhu
    Li, Da
    Pan, Hongming
    Wu, Jun
    Ping, Yuan
    JOURNAL OF GENE MEDICINE, 2019, 21 (07):
  • [24] DNA-free genome editing in tomato protoplasts using CRISPR/Cas9 ribonucleoprotein delivery
    Kang, Ga Hui
    Kang, Beum-Chang
    Han, Jeung-Sul
    Lee, Je Min
    HORTICULTURE ENVIRONMENT AND BIOTECHNOLOGY, 2024, 65 (01) : 131 - 142
  • [25] Efficient Mitochondrial Genome Editing by CRISPR/Cas9
    Jo, Areum
    Ham, Sangwoo
    Lee, Gum Hwa
    Lee, Yun-Il
    Kim, SangSeong
    Lee, Yun-Song
    Shin, Joo-Ho
    Lee, Yunjong
    BIOMED RESEARCH INTERNATIONAL, 2015, 2015
  • [26] DNA-free genome editing in tomato protoplasts using CRISPR/Cas9 ribonucleoprotein delivery
    Ga Hui Kang
    Beum-Chang Kang
    Jeung-Sul Han
    Je Min Lee
    Horticulture, Environment, and Biotechnology, 2024, 65 : 131 - 142
  • [27] Electroporation Delivery of Cas9 sgRNA Ribonucleoprotein-Mediated Genome Editing in Sheep IVF Zygotes
    Pi, Wenhui
    Feng, Guangyu
    Liu, Minghui
    Nie, Cunxi
    Chen, Cheng
    Wang, Jingjing
    Wang, Limin
    Wan, Pengcheng
    Liu, Changbin
    Liu, Yi
    Zhou, Ping
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (17)
  • [28] EFFICIENT GENOME EDITING FOR CORRECTION OF RECESSIVE DYSTROPHIC EPIDERMOLYSIS BULLOSA IN IPS CELLS USING CRISPR/CAS9 RIBONUCLEOPROTEIN COMPLEXES
    Jackow, Joanna
    Guo, Zongyou
    Abaci, Hasan E.
    Doucet, Yanne S.
    Shin, Jung U.
    Hansen, Corey
    Hayashi, Ryota
    Kabata, Yudai
    Shinkuma, Satoru
    Salas-Alanis, Julio C.
    Christiano, Angela M.
    ACTA DERMATO-VENEREOLOGICA, 2020, 100 : 72 - 72
  • [29] Efficient genome editing using CRISPR/Cas9 ribonucleoprotein approach in cultured Medaka fish cells
    Liu, Qizhi
    Yuan, Yongming
    Zhu, Feng
    Hong, Yunhan
    Ge, Ruowen
    BIOLOGY OPEN, 2018, 7 (08):
  • [30] A biodegradable lipid nanoparticle delivers a Cas9 ribonucleoprotein for efficient and safe in situ genome editing in melanoma
    Yang, Xiaopeng
    Zhou, Songli
    Zeng, Jingyi
    Zhang, Suqin
    Li, Meng
    Yue, Feifan
    Chen, Zhaoyi
    Dong, Yanming
    Zeng, Yingchun
    Luo, Jingwen
    ACTA BIOMATERIALIA, 2024, 190 : 531 - 547
12345