SYNTHESIS AND STRUCTURE ELUCIDATION OF BENZOTHIAZOLE-CONTAINING COMPOUNDS FOR ANTIMICROBIAL INVESTIGATION

被引：0
|
作者：
GHONEIM, KM [1 ]
ELBASIL, S [1 ]
OSMAN, AN [1 ]
SAID, MM [1 ]
MEGAHED, SA [1 ]
机构：
[1] UNIV CAIRO,FAC PHARM,DEPT MICROBIOL,CAIRO,EGYPT
来源：
REVUE ROUMAINE DE CHIMIE | 1991年 / 36卷 / 11-12期
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Attempted cycloaddition of benzimidazole-2-thiol with arylidenemalononitriles 1 was unsuccessful. 2-Cyanomethyl-1,3-benzothiazole 6 condensed with certain aromatic aldehydes to produce 7, cycloaddition of which with cyanoacethydrazide 3 yielded B. Structure of the newly synthesized compounds was substantiated by spectroscopic data and/or unambiguous synthesis. Representative compounds were screened for antimicrobial activity.
引用
收藏
页码：1355 / 1361
页数：7
相关论文
共 50 条
  • [41] Design and Synthesis of Polyheterocyclic Compounds Containing Pyrazolopyridopyrimidine Nucleus with Antimicrobial Activities
    El-Essawy, Farag A.
    Odah, Mohammad Ahmad Ahmad
    CHEMISTRYOPEN, 2024, 13 (06)
  • [42] ISOLATION, STRUCTURE ELUCIDATION, AND SYNTHESIS OF AN ANTIMICROBIAL SUBSTANCE FROM PETIVERIA-ALLIACEA L
    SZCZEPAN.CV
    ZGORZELA.P
    HOYER, GA
    ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1972, 22 (11): : 1975 - 1976
  • [43] Synthesis and structure elucidation of new spiro compounds with per(poly)fluoroalkyl group
    Shi Zhi-Jian
    Ni Hua-Wen
    Cao Wei-Guo
    Liu Wei-Xia
    Liang Chao
    CHINESE JOURNAL OF CHEMISTRY, 2006, 24 (07) : 980 - 982
  • [44] Facile Access to Benzothiazole-containing Pyrrolo[1,2-a]quinolines and Pyrrolo[2,1-a]isoquinolines via Nitrogen Ylides
    Dawood, Kamal M.
    Ragab, Eman A.
    Khedr, Nabila A.
    JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2009, 56 (06) : 1180 - 1185
  • [45] Synthesis and Structure Elucidation of New Spiro Compounds with Polyfluoroalkyl and Phosphonate Ester Groups
    Shi, Zhijian
    Zhao, Yang
    Cao, Weiguo
    Zhang, Shunli
    Liu, Mei
    SYNTHETIC COMMUNICATIONS, 2009, 39 (08) : 1494 - 1503
  • [46] A new strategy of enhancing two-photon absorption in benzothiazole-containing fluorene molecules: Introduction of auxiliary donor-acceptor effects
    Ma, Wenbo
    Wu, Yiqun
    Gu, Donghong
    Gan, Fuxi
    JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM, 2006, 774 (1-3): : 13 - 18
  • [47] NEW COMPOUNDS RELATED TO PODOPHYLLOTOXIN AND CONGENERS - SYNTHESIS, STRUCTURE ELUCIDATION AND BIOLOGICAL TESTING
    HANSEN, HF
    JENSEN, RB
    WILLUMSEN, AM
    NORSKOVLAURITSEN, N
    EBBESEN, P
    NIELSEN, PE
    BUCHARDT, O
    ACTA CHEMICA SCANDINAVICA, 1993, 47 (12): : 1190 - 1200
  • [48] Synthesis, characterization and comparative study the microbial activity of some heterocyclic compounds containing oxazole and benzothiazole moieties
    Tomi, Ivan H. R.
    Tomma, Jumbad H.
    Al-Daraji, Ali H. R.
    Al-Dujaili, Ammar H.
    JOURNAL OF SAUDI CHEMICAL SOCIETY, 2015, 19 (04) : 392 - 398
  • [49] Identification, structure elucidation, and synthesis of volatile compounds in the exhaust gas of food factories
    Nagorny, S
    Francke, W
    WASTE MANAGEMENT, 2005, 25 (09) : 880 - 886
  • [50] Synthesis, structure, antimicrobial and antioxidant investigations of dicoumarol and related compounds
    Hamdi, Naceur
    Puerta, M. Carmen
    Valerga, Pedro
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 43 (11) : 2541 - 2548
12345