AUTOANTIBODIES AGAINST FORSSMAN GLYCOLIPIDS IN GRAVES-DISEASE AND HASHIMOTO THYROIDITIS

被引：0

作者：

ARIGA, T ^{[1
]}

YOSHIDA, T ^{[1
]}

MIMORI, T ^{[1
]}

YU, RK ^{[1
]}

机构：

[1] KEIO UNIV,SCH MED,DEPT MED,SHINJUKU KU,TOKYO 108,JAPAN

来源：

CLINICAL AND EXPERIMENTAL IMMUNOLOGY | 1991年 / 86卷 / 03期

关键词：

AUTOIMMUNE DISEASE; GRAVES DISEASE; HASHIMOTO DISEASE; AUTOANTIBODIES; FORSSMAN GLYCOLIPID;

D O I：

暂无

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Sera from patients with Graves' disease and Hashimoto's thyroiditis have been shown to react with the Forssman glycolipid antigen (Gb5) using the techniques of high performance thin-layer chromatography (HPTLC) immunostaining and ELISA. Human monoclonal antibodies (MoAbs) have been prepared by fusion of human myeloma with peripheral lymphocytes from patients with Graves' disease. A MoAb, TRMo-4, reacted strongly and specifically with Gb5. These results suggest that anti-Forssman antibody may be involved in the pathogenesis of these autoimmune diseases. The detection of anti-Forssman glycolipid antibody may provide a useful means for clinical diagnosis and therapy.

引用

页码：483 / 488

页数：6

共 50 条

[11] GRAVES-DISEASE PROGRESSING TO HASHIMOTOS THYROIDITIS
JAFFIOL, C
BALDET, L
PAGES, A
CLOT, J
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1983, 250 (05): : 644 - 645
[12] PATHOGENESIS OF GRAVES-DISEASE AND HASHIMOTOS THYROIDITIS
VOLPE, R
FARID, NR
WESTARP, CV
ROW, VV
CLINICAL ENDOCRINOLOGY, 1974, 3 (03) : 239 - 261
[13] DETECTION AND PROPERTIES OF TSH-BINDING INHIBITOR IMMUNOGLOBULINS IN PATIENTS WITH GRAVES-DISEASE AND HASHIMOTO THYROIDITIS
ENDO, K
KASAGI, K
KONISHI, J
IKEKUBO, K
OKUNO, T
TAKEDA, Y
MORI, T
TORIZUKA, K
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1978, 46 (05): : 734 - 739
[14] THYROID STIMULATING AUTOANTIBODIES IN GRAVES-DISEASE
SCHLEUSENER, H
KOTULLA, P
WENZEL, B
ZEITSCHRIFT FUR IMMUNITATSFORSCHUNG-IMMUNOBIOLOGY, 1979, 156 (03): : 181 - 181
[15] GRAVES-DISEASE ASSOCIATED WITH HISTOLOGIC HASHIMOTOS THYROIDITIS
FALK, SA
BIRKEN, EA
RONQUILLO, AH
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 1985, 93 (01) : 86 - 91
[16] GRAVES-DISEASE WITH THYROTOXICOSIS FOLLOWING SUBACUTE THYROIDITIS
WARTOFSKY, L
SCHAAF, M
AMERICAN JOURNAL OF MEDICINE, 1987, 83 (04): : 761 - 764
[17] PAINLESS SUBACUTE THYROIDITIS SIMULATING GRAVES-DISEASE
BLONDE, L
WITKIN, M
HARRIS, R
WESTERN JOURNAL OF MEDICINE, 1976, 125 (01): : 75 - 78
[18] THE PRODUCTION AND CHARACTERIZATION OF THYROID-DERIVED T-CELL LINES IN GRAVES-DISEASE AND HASHIMOTO THYROIDITIS
WEETMAN, AP
VOLKMAN, DJ
BURMAN, KD
MARGOLICK, JB
PETRICK, P
WEINTRAUB, BD
FAUCI, AS
CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY, 1986, 39 (01): : 139 - 150
[19] HLA ANTIGENS IN GRAVES-DISEASE AND SUBACUTE THYROIDITIS
BECH, K
LUMHOLTZ, B
NERUP, J
THOMSEN, M
PLATZ, P
RYDER, LP
SVEJGARD, A
SIERSBAEKNIELSEN, K
HANSEN, JM
ACTA ENDOCRINOLOGICA, 1976, 82 : 9 - 9
[20] Autoimmune Thyroiditis Shifting from Hashimoto's Thyroiditis to Graves' Disease
Daramjav, Narantsatsral
Takagi, Junko
Iwayama, Hideyuki
Uchino, Kaori
Inukai, Daisuke
Otake, Kazuo
Ogawa, Tetsuya
Takami, Akiyoshi
MEDICINA-LITHUANIA, 2023, 59 (04):

← 1 2 3 4 5 →