In this paper, we prove the connectedness of symplectic ball packings in the complement of a spherical Lagrangian, \documentclass[12pt]{minimal}
\usepackage{amsmath}
\usepackage{wasysym}
\usepackage{amsfonts}
\usepackage{amssymb}
\usepackage{amsbsy}
\usepackage{mathrsfs}
\usepackage{upgreek}
\setlength{\oddsidemargin}{-69pt}
\begin{document}$$S^{2}$$\end{document} or \documentclass[12pt]{minimal}
\usepackage{amsmath}
\usepackage{wasysym}
\usepackage{amsfonts}
\usepackage{amssymb}
\usepackage{amsbsy}
\usepackage{mathrsfs}
\usepackage{upgreek}
\setlength{\oddsidemargin}{-69pt}
\begin{document}$$\mathbb{RP }^{2}$$\end{document}, in symplectic manifolds that are rational or ruled. Via a symplectic cutting construction, this is a natural extension of McDuff’s connectedness of ball packings in other settings and this result has applications to several different questions: smooth knotting and unknottedness results for spherical Lagrangians, the transitivity of the action of the symplectic Torelli group, classifying Lagrangian isotopy classes in the presence of knotting, and detecting Floer-theoretically essential Lagrangian tori in the del Pezzo surfaces.