Correction to: Phase 3 Multicenter Study of Revusiran in Patients with Hereditary Transthyretin-Mediated (hATTR) Amyloidosis with Cardiomyopathy (ENDEAVOUR)

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作者
Daniel P. Judge
Arnt V. Kristen
Martha Grogan
Mathew S. Maurer
Rodney H. Falk
Mazen Hanna
Julian Gillmore
Pushkal Garg
Akshay K. Vaishnaw
Jamie Harrop
Christine Powell
Verena Karsten
Xiaoping Zhang
Marianne T. Sweetser
John Vest
Philip N. Hawkins
机构
[1] Johns Hopkins Hospital,Department of Cardiology
[2] Medical University of South Carolina,National Amyloidosis Centre, Division of Medicine
[3] University of Heidelberg,undefined
[4] Mayo Clinic,undefined
[5] Columbia University Medical Center,undefined
[6] Brigham and Women’s Hospital,undefined
[7] Cleveland Clinic,undefined
[8] UCL Medical School,undefined
[9] Royal Free Hospital,undefined
[10] Rowland Hill Street,undefined
[11] NW3 2PF,undefined
[12] Alnylam Pharmaceuticals,undefined
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The original article contained incorrect terminology for one of the cardiac measures; throughout the manuscript and supplementary information ‘intraventricular septum wall thickness’ should have been given as ‘interventricular septum wall thickness’. Corrections should also be noted for Tables 1 and 4: in the Table 1 legend ‘Low risk – Neither above at baseline’ should read ‘Low risk – Neither above threshold at baseline’; in Table 4, the rows ‘Mild: eGFR > 60 to < 90 ml/min/1.73 m2’ and ‘Moderate: eGFR > 30 to < 60 ml/min/1.73 m2’ should read ‘Mild: eGFR ≥ 60 to < 90 ml/min/1.73 m2’ and ‘Moderate: eGFR ≥ 30 to < 60 ml/min/1.73 m2’, respectively. The original article also contained a mistake in the text of the Pharmacokinetics sub-section of Results; ‘There were no apparent differences in revusiran Cmaxbetween patients with mild (eGFR: 30 and < 60 ml/min/1.73 m2) or moderate (eGFR: 60 to < 90 ml/min/1.73 m2) renal impairment when compared with patients with normal (eGFR: ≥ 90 ml/min/1.73 m2) renal function at Weeks 0, 26, and 52 (p > 0.20) (Supplementary Fig. 6)’ should read ‘There were no apparent differences in revusiran Cmaxbetween patients with mild (eGFR: ≥ 60 to < 90 ml/min/1.73 m2) or moderate (eGFR: ≥ 30 and < 60 ml/min/1.73 m2) renal impairment when compared with patients with normal (eGFR: ≥ 90 ml/min/1.73 m2) renal function at Weeks 0, 26, and 52 (p > 0.20) (Supplementary Fig. 6)’.
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