Aggreganoid G, a New Methylene-Bridged Sesquiterpenoid Dimer from Lindera aggregata

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作者
Songsong Wen
Weijian Wang
Yongjun Liu
Chong Niu
Na Guo
Riran Zhu
Yuwen Xu
机构
[1] Cheeloo College of Medicine,Department of Pharmaceutics, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences
[2] Shandong University,NMPA Key Laboratory for Research and Evaluation of Generic Drugs, Shandong Research Center of Engineering and Technology for Consistency Evaluation of Generic Drugs
[3] Shandong Institute for Food and Drug Control,undefined
[4] Jinan Center for Food and Drug Control,undefined
[5] Affiliated Hospital of Shandong University of Traditional Chinese Medicine,undefined
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关键词
sesquiterpenoid; cytoprotective effect;
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摘要
Aggreganoid G (1), a new methylene-bridged lindenane sesquiterpenoid dimer was isolated and identified from the roots of Lindera aggregata. The structure was elucidated by spectroscopic analysis including MS, IR, 1D, and 2D NMR spectroscopy. The bioactivity evaluation indicated that compound 1 possessed a cytoprotective effect against alcohol-induced oxidative injury in HepG2 cells.
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页码:72 / 74
页数:2
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