Aggreganoid G, a New Methylene-Bridged Sesquiterpenoid Dimer from Lindera aggregata

被引:0
|
作者
Songsong Wen
Weijian Wang
Yongjun Liu
Chong Niu
Na Guo
Riran Zhu
Yuwen Xu
机构
[1] Cheeloo College of Medicine,Department of Pharmaceutics, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences
[2] Shandong University,NMPA Key Laboratory for Research and Evaluation of Generic Drugs, Shandong Research Center of Engineering and Technology for Consistency Evaluation of Generic Drugs
[3] Shandong Institute for Food and Drug Control,undefined
[4] Jinan Center for Food and Drug Control,undefined
[5] Affiliated Hospital of Shandong University of Traditional Chinese Medicine,undefined
来源
关键词
sesquiterpenoid; cytoprotective effect;
D O I
暂无
中图分类号
学科分类号
摘要
Aggreganoid G (1), a new methylene-bridged lindenane sesquiterpenoid dimer was isolated and identified from the roots of Lindera aggregata. The structure was elucidated by spectroscopic analysis including MS, IR, 1D, and 2D NMR spectroscopy. The bioactivity evaluation indicated that compound 1 possessed a cytoprotective effect against alcohol-induced oxidative injury in HepG2 cells.
引用
收藏
页码:72 / 74
页数:2
相关论文
共 50 条
  • [11] Synthesis and X-ray Crystal Structure of a Methylene-bridged Glycoluril Dimer
    She Neng-Fang
    Wu Yan-Dong
    Sun Jing-Jing
    Wu An-Xin
    CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2010, 29 (01) : 47 - 50
  • [12] SYNTHESIS AND STRUCTURE OF NEW METHYLENE-BRIDGED HEXOPYRANOSYL NUCLEOSIDE (BHNA)
    Zhou, Chuanzheng
    Plashkevych, Oleksandr
    Liu, Yi
    Badgujar, Naresh
    Chattopadhyaya, Jyoti
    HETEROCYCLES, 2009, 78 (07) : 1715 - 1728
  • [13] A new sesquiterpene isolated from Lindera aggregata (Sims) Kosterm.
    Cheng, Xian-Long
    Ma, Shuang-Cheng
    Wei, Feng
    Wang, Gang-Li
    Xiao, Xin-Yue
    Lin, Rui-Chao
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2007, 55 (09) : 1390 - 1392
  • [14] PREPARATION OF NEW THIOURACILS VIA RETRODIENE DECOMPOSITION OF METHYLENE-BRIDGED QUINAZOLONETHIONES
    STAJER, G
    SZABO, EA
    PINTYE, J
    BERNATH, G
    SOHAR, P
    MAGYAR KEMIAI FOLYOIRAT, 1986, 92 (01): : 18 - 23
  • [15] Methylene-bridged naphthotubes: new macrocyclic arenes with great potential for supramolecular chemistry
    Yan, Miaomiao
    Zhou, Jiong
    ORGANIC CHEMISTRY FRONTIERS, 2023, 10 (09) : 2340 - 2345
  • [16] Myrrhalindenane C, a New Eudesmane Sesquiterpenoid From Lindera Myrrha Roots
    Hoang-Dung Nguyen
    Huy Truong Nguyen
    Thi-Hoai-Thu Nguyen
    Sichaem, Jirapast
    Huu-Hung Nguyen
    Ngoc-Hong Nguyen
    Thuc-Huy Duong
    RECORDS OF NATURAL PRODUCTS, 2023, 17 (02) : 312 - 317
  • [17] A New Sesquiterpenoid-Geranylbenzene Conjugate from the Roots of Lindera chunii
    Wen, Songsong
    Li, Qiyang
    Liu, Qi
    Dou, Yanli
    Niu, Chong
    Xu, Yuwen
    Zhang, Na
    Wang, Weijian
    CHEMISTRY OF NATURAL COMPOUNDS, 2022, 58 (06) : 1045 - 1047
  • [18] A New Sesquiterpenoid-Geranylbenzene Conjugate from the Roots of Lindera chunii
    Songsong Wen
    Qiyang Li
    Qi Liu
    Yanli Dou
    Chong Niu
    Yuwen Xu
    Na Zhang
    Weijian Wang
    Chemistry of Natural Compounds, 2022, 58 : 1045 - 1047
  • [19] 7-Piperazinylquinolones with methylene-bridged nitrofuran scaffold as new antibacterial agents
    Emami, Saeed
    Shahrokhirad, Nima
    Foroumadi, Alireza
    Faramarzi, Mohammad Ali
    Samadi, Nasrin
    Soltani-Ghofrani, Narges
    MEDICINAL CHEMISTRY RESEARCH, 2013, 22 (12) : 5940 - 5947
  • [20] 7-Piperazinylquinolones with methylene-bridged nitrofuran scaffold as new antibacterial agents
    Saeed Emami
    Nima Shahrokhirad
    Alireza Foroumadi
    Mohammad Ali Faramarzi
    Nasrin Samadi
    Narges Soltani-Ghofrani
    Medicinal Chemistry Research, 2013, 22 : 5940 - 5947