The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers

被引：0
|
作者：
Dinis Pedro Calado
Yoshiteru Sasaki
Susana A Godinho
Alex Pellerin
Karl Köchert
Barry P Sleckman
Ignacio Moreno de Alborán
Martin Janz
Scott Rodig
Klaus Rajewsky
机构：
[1] Program of Cellular and Molecular Medicine,Department of Molecular and Cellular Physiology
[2] Children's Hospital,Department of Pediatric Oncology, Department of Cell Biology
[3] and Immune Disease Institute,Department of Pathology and Immunology
[4] Harvard Medical School,Department of Immunology and Oncology
[5] Max Delbrück Center for Molecular Medicine,Department of Pathology
[6] Graduate School of Medicine,undefined
[7] Kyoto University,undefined
[8] Dana-Farber Cancer Institute,undefined
[9] Harvard Medical School,undefined
[10] Washington University School of Medicine,undefined
[11] National Centre for Biotechnology,undefined
[12] Hematology,undefined
[13] Oncology and Tumor Immunology,undefined
[14] Charité,undefined
[15] University Medical School,undefined
[16] Brigham and Women's Hospital,undefined
来源：
Nature Immunology | 2012年 / 13卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The regulator c-Myc is well known for controlling cell growth but, paradoxically, evidence for its involvement in germinal centers has proven elusive. Rajewsky and colleagues show that it is essential for their development and maintenance.
引用
收藏
页码：1092 / 1100
页数：8
相关论文
共 50 条
  • [31] CELL CYCLE-DEPENDENT ACTIVATION OF C-MYC ENHANCER
    KAKIZAKI, I
    IMAMURA, Y
    GALLI, I
    KIHARA, F
    ARIGA, H
    IGUCHIARIGA, SMM
    INTERNATIONAL JOURNAL OF ONCOLOGY, 1993, 2 (04) : 657 - 661
  • [32] Mysterious liaisons: the relationship between c-Myc and the cell cycle
    Alvaro J Obaya
    Maria K Mateyak
    John M Sedivy
    Oncogene, 1999, 18 : 2934 - 2941
  • [33] Mysterious liaisons: the relationship between c-Myc and the cell cycle
    Obaya, AJ
    Mateyak, MK
    Sedivy, JM
    ONCOGENE, 1999, 18 (19) : 2934 - 2941
  • [34] EFFECT OF NA+ FLUX INHIBITORS ON INDUCTION OF C-FOS, C-MYC, AND ODC GENES DURING CELL-CYCLE
    PANET, R
    AMIR, I
    SNYDER, D
    ZONENSHEIN, L
    ATLAN, H
    LASKOV, R
    PANET, A
    JOURNAL OF CELLULAR PHYSIOLOGY, 1989, 140 (01) : 161 - 168
  • [35] N-Myc and L-Myc are essential for hair cell formation but not maintenance
    Kopecky, Benjamin J.
    DeCook, Rhonda
    Fritzsch, Bernd
    BRAIN RESEARCH, 2012, 1484 : 1 - 14
  • [36] Overexpression of c-Myc and cell immortalization alters c-Myc phosphorylation
    Bart Lutterbach
    Stephen R Hann
    Oncogene, 1997, 14 : 967 - 975
  • [37] Overexpression of c-Myc and cell immortalization alters c-Myc phosphorylation
    Lutterbach, B
    Hann, SR
    ONCOGENE, 1997, 14 (08) : 967 - 975
  • [38] INTERLEUKIN-3 DEPENDENT C-MYC PROTEIN EXPRESSION DURING THE CELL-CYCLE OF MURINE MAST-CELLS
    MINKS, M
    DIVINCI, A
    BRUNO, S
    GEIDO, E
    AVIGNOLO, C
    GIARETTI, W
    CANCER LETTERS, 1992, 62 (03) : 243 - 249
  • [39] Cell cycle activation by c-myc in a Burkitt lymphoma model cell line
    Pajic, A
    Spitkovsky, D
    Christoph, B
    Kempkes, B
    Schuhmacher, M
    Staege, MS
    Brielmeier, M
    Ellwart, J
    Kohlhuber, F
    Bornkamm, GW
    Polack, A
    Eick, D
    INTERNATIONAL JOURNAL OF CANCER, 2000, 87 (06) : 787 - 793
  • [40] Stabilization of c-Myc by the atypical cell cycle regulator, Spy1, decreases efficacy of breast cancer treatments
    Ferraiuolo, Rosa-Maria
    Fifield, Bre-Anne
    Hamm, Caroline
    Porter, Lisa A.
    BREAST CANCER RESEARCH AND TREATMENT, 2022, 196 (01) : 17 - 30
12345