The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers

被引：0
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作者：
Dinis Pedro Calado
Yoshiteru Sasaki
Susana A Godinho
Alex Pellerin
Karl Köchert
Barry P Sleckman
Ignacio Moreno de Alborán
Martin Janz
Scott Rodig
Klaus Rajewsky
机构：
[1] Program of Cellular and Molecular Medicine,Department of Molecular and Cellular Physiology
[2] Children's Hospital,Department of Pediatric Oncology, Department of Cell Biology
[3] and Immune Disease Institute,Department of Pathology and Immunology
[4] Harvard Medical School,Department of Immunology and Oncology
[5] Max Delbrück Center for Molecular Medicine,Department of Pathology
[6] Graduate School of Medicine,undefined
[7] Kyoto University,undefined
[8] Dana-Farber Cancer Institute,undefined
[9] Harvard Medical School,undefined
[10] Washington University School of Medicine,undefined
[11] National Centre for Biotechnology,undefined
[12] Hematology,undefined
[13] Oncology and Tumor Immunology,undefined
[14] Charité,undefined
[15] University Medical School,undefined
[16] Brigham and Women's Hospital,undefined
来源：
Nature Immunology | 2012年 / 13卷
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摘要：
The regulator c-Myc is well known for controlling cell growth but, paradoxically, evidence for its involvement in germinal centers has proven elusive. Rajewsky and colleagues show that it is essential for their development and maintenance.
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页码：1092 / 1100
页数：8
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