Solvent-free microwave assisted synthesis of (E)-1-{3-[2-(9-Ethyl-9H-carbazol-3-yl)vinyl]benzofuran-2-yl}-2,2-dimethylpropan-1-ones and their antimicrobial activity

被引：8
|
作者：
Ashok, D. [1 ]
Sidda, Ravi [1 ]
Lakshmi, B. Vijaya [1 ]
Ganesh, Arram [1 ]
机构：
[1] Osmania Univ, Dept Chem, Hyderabad 500007, Andhra Pradesh, India
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2014年 / 84卷 / 11期
关键词：
microwave assisted synthesis; carbazole-3-carbaldehyde; carbazolylaryl prop-2-enones; carbazolylvinylbenzofurans; antimicrobial activity; CHALCONES; DERIVATIVES; BENZOFURAN;
D O I：
10.1134/S1070363214110280
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report the solvent-free synthesis of (E)-1-{3-[2-(9-Ethyl-9H-carbazol-3-yl)vinyl]benzofuran-2-yl}-2,2-dimethylpropan-1-ones starting with 9-Ethyl-9H-carbazole-3-carbaldehyde under conventional and microwave irradiation methods. All products were characterised by IR, H-1 NMR, C-13 NMR, mass spectrometry, and elemental analysis. The compounds were tested in vitro for their antimicrobial activity.
引用
收藏
页码：2211 / 2217
页数：7
相关论文
共 50 条
  • [41] Synthesis of 2-(9H-carbazol-1-yl)anilines from 2,3′-biindolyl and ketones
    Noland, Wayland E.
    Brown, Christopher D.
    Zabronsky, Abigail E.
    Tritch, Kenneth J.
    TETRAHEDRON, 2018, 74 (19) : 2391 - 2404
  • [42] Mild synthesis of 5-(9-ethyl-9H-carbazol-3-yl)-N-aryl-1,3,4-thiadiazol-2-amines
    Li, Zheng
    Xing, Yulin
    RESEARCH ON CHEMICAL INTERMEDIATES, 2012, 38 (09) : 2223 - 2228
  • [43] Mild synthesis of 5-(9-ethyl-9H-carbazol-3-yl)-N-aryl-1,3,4-thiadiazol-2-amines
    Zheng Li
    Yulin Xing
    Research on Chemical Intermediates, 2012, 38 : 2223 - 2228
  • [44] 1-(1-Hydroxy-9H-carbazol-2-yl)-3-methylbut-2-en-1-one
    Zeller, Matthias
    Sridharan, Makuteswaran
    Prasad, Karnam J. Rajendra
    Ngendahimana, Aimable
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O297 - U1859
  • [45] Microwave-assisted synthesis of 1-{2-[(1-benzyl-1H-1,2,3-triazol-4-yl)methoxy]phenyl}-3-(3-aryl-1-phenyl-1H-pyrazol-4-yl)prop-2-en-1-ones and their antimicrobial activity
    D. Ashok
    K. Padmavati
    Russian Journal of General Chemistry, 2016, 86 : 907 - 914
  • [46] Synthesis of Derivatives of 1-(9-Alkyl-9H-carbazol-3-yl)-4-carboxy-2-pyrrolidinones
    B. Sapiyanskaite
    V. Mickevicius
    G. Mikulskene
    Chemistry of Heterocyclic Compounds, 2003, 39 (9) : 1142 - 1152
  • [47] Microwave-assisted synthesis of 1-{2-[(1-benzyl-1H-1,2,3-triazol-4-yl)methoxy]phenyl}-3-(3-aryl-1-phenyl-1H-pyrazol-4-yl)prop-2-en-1-ones and their antimicrobial activity
    Ashok, D.
    Padmavati, K.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2016, 86 (04) : 907 - 914
  • [48] Synthesis of 1-(9-alkyl-9H-carbazol-3-yl)-4-carboxy-2-pyrrolidinone derivatives
    Sapijanskaite, B
    Mickevicius, V
    Mikulskiene, G
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 2003, (09): : 1305 - 1315
  • [49] Ethyl 2-(9-methylsulfonyl-1-oxo-2,3,4,9-tetrahydro-1H-carbazol-2-yl)acetate
    Ozbey, Suheyla
    Karayel, Arzu
    Yilmaz, Ayhan
    Uludag, Nesimi
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O1623 - O1625
  • [50] SYNTHESIS AND PHARMACODYNAMIC ACTIVITY OF 2-(3-(2-PHENYLETHYL)BENZOFURAN-2-YL)-N-PROPYL-ETHANAMINE
    ECKER, G
    HELML, T
    FLEISCHHACKER, W
    NOE, CR
    STUDENIK, C
    SCHADE, B
    HEISTRACHER, P
    ARCHIV DER PHARMAZIE, 1995, 328 (04) : 343 - 348
12345