Nonpathogenic Bacteria as Targets in Antimicrobial High-Throughput Screening

被引:0
|
作者
Yague, Paula [1 ]
Gonzalez-Quinonez, Nathaly [1 ]
Manteca, Angel [1 ]
机构
[1] Univ Oviedo, Area Microbiol, Dept Biol Func, IUOPA,ISPA,Fac Med, E-33006 Oviedo, Spain
基金
欧洲研究理事会;
关键词
STREPTOMYCES;
D O I
10.1016/j.tim.2019.10.005
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Antimicrobial screening usually analyses the effects of natural or synthetic molecules against pathogens. McAuley et al. changed this paradigm, testing the effect of synthetic compounds against the sporulation of the nonpathogenic bacterium Streptomyces venezuelae. They discovered a novel DNA-targeting antibiotic effective against pathogens.
引用
收藏
页码:1 / 2
页数:2
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