Nonpathogenic Bacteria as Targets in Antimicrobial High-Throughput Screening

被引:0
|
作者
Yague, Paula [1 ]
Gonzalez-Quinonez, Nathaly [1 ]
Manteca, Angel [1 ]
机构
[1] Univ Oviedo, Area Microbiol, Dept Biol Func, IUOPA,ISPA,Fac Med, E-33006 Oviedo, Spain
基金
欧洲研究理事会;
关键词
STREPTOMYCES;
D O I
10.1016/j.tim.2019.10.005
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Antimicrobial screening usually analyses the effects of natural or synthetic molecules against pathogens. McAuley et al. changed this paradigm, testing the effect of synthetic compounds against the sporulation of the nonpathogenic bacterium Streptomyces venezuelae. They discovered a novel DNA-targeting antibiotic effective against pathogens.
引用
收藏
页码:1 / 2
页数:2
相关论文
共 50 条
  • [31] Conjugated Polythiophene for Rapid, Simple, and High-Throughput Screening of Antimicrobial Photosensitizers
    Li, Ruihua
    Niu, Ruimin
    Qi, Junjie
    Yuan, Hongbo
    Fan, Yibing
    An, Hailong
    Yan, Wenmin
    Li, Huanrong
    Zhan, Yong
    Xing, Chengfen
    ACS APPLIED MATERIALS & INTERFACES, 2015, 7 (27) : 14569 - 14572
  • [32] High-throughput screening with transcriptomics
    Singh, Arunima
    NATURE METHODS, 2020, 17 (03) : 251 - 251
  • [33] High-throughput virtual screening
    Hirata, Shuzo
    Shizu, Katsuyuki
    NATURE MATERIALS, 2016, 15 (10) : 1056 - 1057
  • [34] High-throughput screening analysis
    不详
    R&D MAGAZINE, 1997, 39 (08): : 47 - 47
  • [35] High-throughput screening on microchips
    Chow, A
    Kopf-Sill, A
    Nikiforov, T
    Zhou, A
    Coffin, J
    Wada, G
    Alajoki, L
    Spaid, M
    Yurkovetsky, Y
    Sundberg, S
    Parce, JW
    MICRO TOTAL ANALYSIS SYSTEMS 2000, PROCEEDINGS, 2000, : 489 - 492
  • [36] High-Throughput Hybridoma Screening
    Sawyer, Alan
    Hall, Duncan
    GENETIC ENGINEERING & BIOTECHNOLOGY NEWS, 2011, 31 (05): : 28 - +
  • [37] High-throughput screening with transcriptomics
    Lei Tang
    Nature Methods, 2020, 17 : 251 - 251
  • [38] High-throughput screening with aptamers
    不详
    BIOTECHNIQUES, 2001, 30 (05) : 913 - 913
  • [39] High-throughput ADE screening
    Kretz, O
    Probst, A
    PHARMACOKINETIC OPTIMIZATION IN DRUG RESEARCH: BIOLOGICAL, PHYSICOCHEMICAL, AND COMPUTATIONAL STRATEGIES, 2001, : 199 - 215