Nonpathogenic Bacteria as Targets in Antimicrobial High-Throughput Screening

被引：0

作者：

Yague, Paula ^{[1
]}

Gonzalez-Quinonez, Nathaly ^{[1
]}

Manteca, Angel ^{[1
]}

机构：

[1] Univ Oviedo, Area Microbiol, Dept Biol Func, IUOPA,ISPA,Fac Med, E-33006 Oviedo, Spain

来源：

TRENDS IN MICROBIOLOGY | 2020年 / 28卷 / 01期

基金：

欧洲研究理事会;

关键词：

STREPTOMYCES;

D O I：

10.1016/j.tim.2019.10.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Antimicrobial screening usually analyses the effects of natural or synthetic molecules against pathogens. McAuley et al. changed this paradigm, testing the effect of synthetic compounds against the sporulation of the nonpathogenic bacterium Streptomyces venezuelae. They discovered a novel DNA-targeting antibiotic effective against pathogens.

引用

页码：1 / 2

页数：2

共 50 条

[21] High-throughput screening
Nature, 2001, 413 (6855) : 549 - 550
[22] High-throughput screening
Rogers, MV
DRUG DISCOVERY TODAY, 1997, 2 (07) : 306 - 306
[23] High-throughput screening for molecular targets in relapse into alcohol dependence.
Littleton, J. M.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2006, 30 (06) : 277A - 277A
[24] Application of small molecule microarrays in high-throughput screening of protein targets
Uttamchandani, Mahesh
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 240
[25] High-throughput platforms for the screening of new therapeutic targets for neurodegenerative diseases
Rocha, Daniela N.
Carvalho, Eva D.
Pego, Ana Paula
DRUG DISCOVERY TODAY, 2016, 21 (09) : 1355 - 1366
[26] Advances in functional assays for high-throughput screening of ion channels targets
Trivedi, Shephali
Liu, Jay
Liu, Ruifeng
Bostwick, Robert
EXPERT OPINION ON DRUG DISCOVERY, 2010, 5 (10) : 995 - 1006
[27] A high-throughput expression screening platform to optimize the production of antimicrobial peptides
Christine Schreiber
Hagen Müller
Oliver Birrenbach
Moritz Klein
Doreen Heerd
Tobias Weidner
Denise Salzig
Peter Czermak
Microbial Cell Factories, 16
[28] A high-throughput expression screening platform to optimize the production of antimicrobial peptides
Schreiber, Christine
Mueller, Hagen
Birrenbach, Oliver
Klein, Moritz
Heerd, Doreen
Weidner, Tobias
Salzig, Denise
Czermak, Peter
MICROBIAL CELL FACTORIES, 2017, 16
[29] Rapid, Simple, and High-Throughput Antimicrobial Susceptibility Testing and Antibiotics Screening
Zhu, Chunlei
Yang, Qiong
Liu, Libing
Wang, Shu
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (41) : 9607 - 9610
[30] Conjugated polythiophene for rapid, simple and high-throughput screening of antimicrobial photosensitizers
Li, Ruihua
Niu, Ruimin
Xing, Chengfen
Yuan, Hongbo
Chai, Ran
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252

← 1 2 3 4 5 →