Blunt-ended DNA stacking interactions in a 3-helix motif

被引：34

作者：

Wang, Risheng ^{[1
]}

Kuzuya, Akinori ^{[2
]}

Liu, Wenyan ^{[1
]}

Seeman, Nadrian C. ^{[1
]}

机构：

[1] NYU, Dept Chem, New York, NY 10003 USA

[2] Univ Tokyo, Res Ctr Adv Sci & Technol, Meguro Ku, Tokyo 1538904, Japan

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 27期

基金：

美国国家科学基金会;

关键词：

CRYSTALS; MOLECULE; PROTEIN; DESIGN;

D O I：

10.1039/c0cc01167c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We demonstrate that intermolecular stacking is capable of forming one-dimensional arrays of a blunt-ended 3-helix DNA motif. The array can be visualized in the atomic force microscopy through conjugated streptavidin nanoparticles. We estimate the strength of the triple stacking interaction to be -8.6 kcal mol(-1).

引用

页码：4905 / 4907

页数：3

共 33 条

[31] Cooperative interactions between the two DNA binding domains of Pax3: Helix 2 of the paired domain is in the proximity of the amino terminus of the homeodomain
Apuzzo, Sergio
Gros, Philippe
BIOCHEMISTRY, 2007, 46 (11) : 2984 - 2993
[32] Differential Base Stacking Interactions Induced by Trimethylene Interstrand DNA Cross-Links in the 5′-CpG-3′ and 5′-GpC-3′ Sequence Contexts
Huang, Hai
Dooley, Patricia A.
Harris, Constance M.
Harris, Thomas M.
Stone, Michael P.
CHEMICAL RESEARCH IN TOXICOLOGY, 2009, 22 (11) : 1810 - 1816
[33] RAMAN SPECTRAL STUDIES OF NUCLEIC-ACIDS .42. DNA RECOGNITION BY THE HELIX-TURN-HELIX MOTIF - INVESTIGATION BY LASER RAMAN-SPECTROSCOPY OF THE PHAGE LAMBDA REPRESSOR AND ITS INTERACTION WITH OPERATOR SITES OL1 AND OR3
BENEVIDES, JM
WEISS, MA
THOMAS, GJ
BIOCHEMISTRY, 1991, 30 (24) : 5955 - 5963

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