Blunt-ended DNA stacking interactions in a 3-helix motif

被引:34
|
作者
Wang, Risheng [1 ]
Kuzuya, Akinori [2 ]
Liu, Wenyan [1 ]
Seeman, Nadrian C. [1 ]
机构
[1] NYU, Dept Chem, New York, NY 10003 USA
[2] Univ Tokyo, Res Ctr Adv Sci & Technol, Meguro Ku, Tokyo 1538904, Japan
基金
美国国家科学基金会;
关键词
CRYSTALS; MOLECULE; PROTEIN; DESIGN;
D O I
10.1039/c0cc01167c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We demonstrate that intermolecular stacking is capable of forming one-dimensional arrays of a blunt-ended 3-helix DNA motif. The array can be visualized in the atomic force microscopy through conjugated streptavidin nanoparticles. We estimate the strength of the triple stacking interaction to be -8.6 kcal mol(-1).
引用
收藏
页码:4905 / 4907
页数:3
相关论文
共 33 条
  • [21] DNA recognition for virus assembly through multiple sequence-independent interactions with a helix-turn-helix motif
    Greive, Sandra J.
    Fung, Herman K. H.
    Chechik, Maria
    Jenkins, Huw T.
    Weitzel, Stephen E.
    Aguiar, Pedro M.
    Brentnall, Andrew S.
    Glousieau, Matthieu
    Gladyshev, Grigory V.
    Potts, Jennifer R.
    Antson, Alfred A.
    NUCLEIC ACIDS RESEARCH, 2016, 44 (02) : 776 - 789
  • [22] THE 3-WAY DNA JUNCTION IS A Y-SHAPED MOLECULE IN WHICH THERE IS NO HELIX HELIX STACKING
    DUCKETT, DR
    LILLEY, DMJ
    EMBO JOURNAL, 1990, 9 (05): : 1659 - 1664
  • [23] DNA with hydrophobic base substitutes: A stable, zipperlike recognition motif based on interstrand-stacking interactions
    Brotschi, C
    Leumann, CJ
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2003, 42 (14) : 1655 - 1658
  • [24] Cy3-DNA Stacking Interactions Strongly Depend on the Identity of the Terminal Basepair
    Spiriti, Justin
    Binder, Jennifer K.
    Levitus, Marcia
    van der Vaart, Arjan
    BIOPHYSICAL JOURNAL, 2011, 100 (04) : 1049 - 1057
  • [25] EFFECT OF THE ENVIRONMENT AND ROLE OF THE PI-PI STACKING INTERACTIONS IN THE STABILIZATION OF THE 3(10)-HELIX CONFORMATION IN DEHYDROALANINE OLIGOPEPTIDES
    ALEMAN, C
    INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, 1995, 46 (05): : 408 - 418
  • [26] Sequence dependence of BNIP3 transmembrane domain dimerization implicates side-chain hydrogen bonding and a tandem GxxxG motif in specific helix-helix interactions
    Sulistijo, Endah S.
    MacKenzie, Kevin R.
    JOURNAL OF MOLECULAR BIOLOGY, 2006, 364 (05) : 974 - 990
  • [27] Experimental verification of theoretical predictions of Cy3-DNA stacking interactions that depend on the terminal base pair
    Binder, Jennifer K.
    Spiriti, Justin
    Levitus, Marcia
    van der Vaart, Arjan
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 242
  • [28] Structural Studies of E73 from a Hyperthermophilic Archaeal Virus Identify the "RH3" Domain, an Elaborated Ribbon-Helix-Helix Motif Involved in DNA Recognition
    Schlenker, Casey
    Goel, Anupam
    Tripet, Brian P.
    Menon, Smita
    Willi, Taylor
    Dlakic, Mensur
    Young, Mark J.
    Lawrence, C. Martin
    Copie, Valerie
    BIOCHEMISTRY, 2012, 51 (13) : 2899 - 2910
  • [29] Theoretical investigation of the backbone•••π and π•••π stacking interactions in substituted-benzene||3-methyl-2′-deoxyadenosine: a perspective to the DNA repair
    Delarami, Hojat Samareh
    Ebrahimi, Ali
    MOLECULAR PHYSICS, 2016, 114 (06) : 774 - 783
  • [30] Sequence-dependent interactions of two forms of UvrC with DNA helix-stabilizing CC-1065-N3-adenine adducts
    Nazimiec, M
    Lee, CS
    Tang, YL
    Ye, XC
    Case, R
    Tang, M
    BIOCHEMISTRY, 2001, 40 (37) : 11073 - 11081