Synthesis of 1,2,4-triazole-3-thiols and their S-substituted derivatives

被引：11

作者：

Kochikyan, T. V. ^{[1
]}

Samvelyan, M. A. ^{[1
]}

Arutyunyan, V. S. ^{[1
]}

Avetisyan, A. A. ^{[1
]}

Tamazyan, R. A. ^{[2
]}

Aivazyan, A. G. ^{[2
]}

机构：

[1] Erevan State Univ, Yerevan 375025, Armenia

[2] Natl Acad Sci Armenia, Sci Technol Ctr Organ & Pharmaceut Chem, Mol Struct Res Ctr, Yerevan 375014, Armenia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 46卷 / 04期

关键词：

Benzyl Chloride; Anhydrous Potassium Carbonate; Carbazide; Phenoxymethyl; Carboxylic Acid Hydrazide;

D O I：

10.1134/S1070428010040184

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New 1,2,4-triazole-3-thiols were synthesized by reactions of the corresponding carboxylic acid hydrazides with isothiocyanates and subsequent cyclization of intermediate 1,4-substituted thiosemicarbazides. Alkylation of 1,2,4-triazole-3-thiols with benzyl chlorides and bromacetophenones gave only S-substituted derivatives.

引用

页码：551 / 555

页数：5

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