Synthesis of 1,2,4-triazole-3-thiols and their S-substituted derivatives

被引：11
|
作者：
Kochikyan, T. V. [1 ]
Samvelyan, M. A. [1 ]
Arutyunyan, V. S. [1 ]
Avetisyan, A. A. [1 ]
Tamazyan, R. A. [2 ]
Aivazyan, A. G. [2 ]
机构：
[1] Erevan State Univ, Yerevan 375025, Armenia
[2] Natl Acad Sci Armenia, Sci Technol Ctr Organ & Pharmaceut Chem, Mol Struct Res Ctr, Yerevan 375014, Armenia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 46卷 / 04期
关键词：
Benzyl Chloride; Anhydrous Potassium Carbonate; Carbazide; Phenoxymethyl; Carboxylic Acid Hydrazide;
D O I：
10.1134/S1070428010040184
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
New 1,2,4-triazole-3-thiols were synthesized by reactions of the corresponding carboxylic acid hydrazides with isothiocyanates and subsequent cyclization of intermediate 1,4-substituted thiosemicarbazides. Alkylation of 1,2,4-triazole-3-thiols with benzyl chlorides and bromacetophenones gave only S-substituted derivatives.
引用
收藏
页码：551 / 555
页数：5
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