Size distribution of virus laden droplets from expiratory ejecta of infected subjects
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作者:
Anand, S.
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Bhabha Atom Res Ctr, Div Hlth Phys, Mumbai 400085, Maharashtra, India
Bhabha Atom Res Ctr, Homi Bhabha Natl Inst, Mumbai 400094, Maharashtra, IndiaBhabha Atom Res Ctr, Div Hlth Phys, Mumbai 400085, Maharashtra, India
Anand, S.
[1
,2
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Mayya, Y. S.
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Indian Inst Technol, Dept Chem Engn, Mumbai 400076, Maharashtra, IndiaBhabha Atom Res Ctr, Div Hlth Phys, Mumbai 400085, Maharashtra, India
Mayya, Y. S.
[3
]
机构:
[1] Bhabha Atom Res Ctr, Div Hlth Phys, Mumbai 400085, Maharashtra, India
[2] Bhabha Atom Res Ctr, Homi Bhabha Natl Inst, Mumbai 400094, Maharashtra, India
[3] Indian Inst Technol, Dept Chem Engn, Mumbai 400076, Maharashtra, India
For rebooting economic activities in the ongoing COVID-19 pandemic scenario, it is important to pay detailed attention to infection transfer mechanisms during interaction of people in enclosed environments. Utmost concern is the possibility of aerosol mediated infection transfer, which is largely governed by the size distributions of virus laden droplets, termed as virusols in this work, ejected from humans. We expand on the well-known theory of Poisson fluctuations which acts as statistical barrier against formation of virusols. Analysis suggests that for viral loads < 2 x 10(5) RNA copies/mL, often corresponding to mild-to-moderate cases of COVID-19, droplets of diameter < 20 mu m at the time of emission (equivalent to similar to 10 mu m desiccated residue diameter) are unlikely to be of consequence in carrying infections. Cut-off diameters below which droplets will be practically free of contamination, are presented as a function of viral loading. The median diameters of virus laden polydisperse droplet distributions will be 1.5 to 20 times higher depending upon the geometric standard deviation. The studies have implications to risk assessment as well as residence time estimates of airborne infections in indoor environments. Additionally, it will be also helpful for performance evaluation of sanitization and control technologies to mitigate infection risks in workplaces.
机构:
Department of Electrical and Mechanical Engineering, Nagoya Institute of Technology, Showa-ku, NagoyaDepartment of Electrical and Mechanical Engineering, Nagoya Institute of Technology, Showa-ku, Nagoya
Nishida M.
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Hayashi K.
Higashide M.
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机构:
Research and Development Direct., JAXA, Shindai-ji, Chofu, TokyoDepartment of Electrical and Mechanical Engineering, Nagoya Institute of Technology, Showa-ku, Nagoya
机构:
Univ Gadjah Mada, Fac Vet Med, Vet Sci Doctoral Study Program, Yogyakarta 55281, Indonesia
Dis Invest Ctr Lampung, Jalan Untung Suropati Bandar Lampung, Lampung 35142, IndonesiaUniv Gadjah Mada, Fac Vet Med, Vet Sci Doctoral Study Program, Yogyakarta 55281, Indonesia
Angeliya, Liza
Kristianingrum, Yuli Purwandari
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Univ Gadjah Mada, Fac Vet Med, Dept Pathol, Yogyakarta 55281, IndonesiaUniv Gadjah Mada, Fac Vet Med, Vet Sci Doctoral Study Program, Yogyakarta 55281, Indonesia
Kristianingrum, Yuli Purwandari
Asmara, Widya
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Univ Gadjah Mada, Fac Vet Med, Dept Microbiol, Yogyakarta 55281, IndonesiaUniv Gadjah Mada, Fac Vet Med, Vet Sci Doctoral Study Program, Yogyakarta 55281, Indonesia
Asmara, Widya
Wibowo, Michael Haryadi
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Univ Gadjah Mada, Fac Vet Med, Dept Microbiol, Yogyakarta 55281, IndonesiaUniv Gadjah Mada, Fac Vet Med, Vet Sci Doctoral Study Program, Yogyakarta 55281, Indonesia