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Predicting postoperative liver cancer death outcomes with machine learning
被引:15
|作者:
Wang, Yong
[1
]
Ji, Chaopeng
[2
,3
]
Wang, Ying
[1
]
Ji, Muhuo
[1
]
Yang, Jian-Jun
[1
]
Zhou, Cheng-Mao
[1
]
机构:
[1] Zhengzhou Univ, Affiliated Hosp 1, Dept Anesthesiol Pain & Perioperat Med, Zhengzhou, Peoples R China
[2] Zhengzhou Univ, Affiliated Hosp 1, Dept Rehabil Med, Zhengzhou, Peoples R China
[3] Zhengzhou Univ, Med Coll, Zhengzhou, Peoples R China
基金:
中国国家自然科学基金;
关键词:
Machine learning;
hepatocellular carcinoma;
mortality;
postoperative;
AUC;
D O I:
10.1080/03007995.2021.1885361
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Objective To investigate the effect of 5 machine learning algorithms in predicting total hepatocellular carcinoma (HCC) postoperative death outcomes. Methods This study was a secondary analysis. A prognosis model was established using machine learning with python. Results The results from the machine learning gbm algorithm showed that the most important factors, ranked from first to fifth, were: preoperative aspartate aminotransferase (GOT), preoperative AFP, preoperative cereal third transaminase (GPT), preoperative total bilirubin, and LC3. Postoperative death model results for liver cancer patients in the test group: of the 5 algorithm models, the highest accuracy rate was that of forest (0.739), followed by the gbm algorithm (0.714); of the 5 algorithms, the AUC values, from high to low, were forest (0.803), GradientBoosting (0.746), gbm (0.724), Logistic (0.660) and DecisionTree (0.578). Conclusion Machine learning can predict total hepatocellular carcinoma postoperative death outcomes.
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页码:629 / 634
页数:6
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