Predicting postoperative liver cancer death outcomes with machine learning

被引:15
|
作者
Wang, Yong [1 ]
Ji, Chaopeng [2 ,3 ]
Wang, Ying [1 ]
Ji, Muhuo [1 ]
Yang, Jian-Jun [1 ]
Zhou, Cheng-Mao [1 ]
机构
[1] Zhengzhou Univ, Affiliated Hosp 1, Dept Anesthesiol Pain & Perioperat Med, Zhengzhou, Peoples R China
[2] Zhengzhou Univ, Affiliated Hosp 1, Dept Rehabil Med, Zhengzhou, Peoples R China
[3] Zhengzhou Univ, Med Coll, Zhengzhou, Peoples R China
基金
中国国家自然科学基金;
关键词
Machine learning; hepatocellular carcinoma; mortality; postoperative; AUC;
D O I
10.1080/03007995.2021.1885361
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective To investigate the effect of 5 machine learning algorithms in predicting total hepatocellular carcinoma (HCC) postoperative death outcomes. Methods This study was a secondary analysis. A prognosis model was established using machine learning with python. Results The results from the machine learning gbm algorithm showed that the most important factors, ranked from first to fifth, were: preoperative aspartate aminotransferase (GOT), preoperative AFP, preoperative cereal third transaminase (GPT), preoperative total bilirubin, and LC3. Postoperative death model results for liver cancer patients in the test group: of the 5 algorithm models, the highest accuracy rate was that of forest (0.739), followed by the gbm algorithm (0.714); of the 5 algorithms, the AUC values, from high to low, were forest (0.803), GradientBoosting (0.746), gbm (0.724), Logistic (0.660) and DecisionTree (0.578). Conclusion Machine learning can predict total hepatocellular carcinoma postoperative death outcomes.
引用
收藏
页码:629 / 634
页数:6
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