Explainable Artificial Intelligence for COVID-19 Diagnosis Through Blood Test Variables

被引:16
|
作者
Thimoteo, Lucas M. [1 ]
Vellasco, Marley M. [1 ]
Amaral, Jorge [2 ]
Figueiredo, Karla [3 ]
Yokoyama, Catia Lie [4 ]
Marques, Erito [2 ]
机构
[1] Pontificia Univ Catolica Rio de Janeiro, Dept Engn Elect, Rio De Janeiro, RJ, Brazil
[2] Univ Estado Rio de Janeiro, Programa Posgrad Engn Eletron PEL, Rio De Janeiro, RJ, Brazil
[3] Univ Estado Rio de Janeiro, Programa Posgrad Telessaude, Programa Posgrad Ciencias Computacionais CCOMP, Rio De Janeiro, RJ, Brazil
[4] Univ Estadual Londrina, Dept Biol Geral, Londrina, Parana, Brazil
关键词
COVID-19; diagnosis; Machine learning; Explainability; Interpretability; Shapley additive explanations; Explainable boosting machine; CYTOKINE STORM; SARS-COV-2;
D O I
10.1007/s40313-021-00858-y
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
This work proposes an explainable artificial intelligence approach to help diagnose COVID-19 patients based on blood test and pathogen variables. Two glass-box models, logistic regression and explainable boosting machine, and two black-box models, random forest and support vector machine, were used to assess the disease diagnosis. Shapley additive explanations were used to explain predictions for the black-box models, while glass-box models feature importance brought insights into the most relevant features. All global explanations show the eosinophils and leukocytes, white blood cells are among the essential features to help diagnose the COVID-19. Moreover, the best model obtained an AUC of 0.87.
引用
收藏
页码:625 / 644
页数:20
相关论文
共 50 条
  • [31] Artificial Intelligence in the Era of COVID-19
    Gupta, Sonia
    APPLIED RADIOLOGY, 2020, 49 (04) : 36 - 37
  • [32] Artificial intelligence in the control of COVID-19
    Gamero, Aldo Medina
    Chamorro, Monica Regalado
    ATENCION PRIMARIA, 2021, 53 (10):
  • [33] COVID-19 Artificial Intelligence Diagnosis Using Only Cough Recordings
    Laguarta, Jordi
    Hueto, Ferran
    Subirana, Brian
    IEEE OPEN JOURNAL OF ENGINEERING IN MEDICINE AND BIOLOGY, 2020, 1 (01): : 275 - 281
  • [34] The value of artificial intelligence and imaging diagnosis in the fight against COVID-19
    Zhang D.
    Liu X.
    Shao M.
    Sun Y.
    Lian Q.
    Zhang H.
    Personal and Ubiquitous Computing, 2023, 27 (03) : 783 - 792
  • [35] Artificial Intelligence in Pharmacovigilance and COVID-19
    Bhardwaj, Kamini
    Alam, Rabnoor
    Pandeya, Ajay
    Sharma, Pankaj Kumar
    CURRENT DRUG SAFETY, 2023, 18 (01) : 5 - 14
  • [36] Artificial Intelligence and COVID-19: Deep Learning Approaches for Diagnosis and Treatment
    Jamshidi, Mohammad Behdad
    Lalbakhsh, Ali
    Talla, Jakub
    Peroutka, Zdenek
    Hadjilooei, Farimah
    Lalbakhsh, Pedram
    Jamshidi, Morteza
    La Spada, Luigi
    Mirmozafari, Mirhamed
    Dehghani, Mojgan
    Sabet, Asal
    Roshani, Saeed
    Roshani, Sobhan
    Bayat-Makou, Nima
    Mohamadzade, Bahare
    Malek, Zahra
    Jamshidi, Alireza
    Kiani, Sarah
    Hashemi-Dezaki, Hamed
    Mohyuddin, Wahab
    IEEE ACCESS, 2020, 8 : 109581 - 109595
  • [37] Potential of artificial intelligence to accelerate diagnosis and drug discovery for COVID-19
    Mikkili, Indira
    Karlapudi, Abraham Peele
    Venkateswarulu, T. C.
    Kodali, Vidya Prabhakar
    Macamdas, Deepika Sri Singh
    Sreerama, Krupanidhi
    PEERJ, 2021, 9
  • [38] Explainable artificial intelligence-based edge fuzzy images for COVID-19 detection and identification
    Hu, Qinhua
    Gois, Francisco Nauber B.
    Costa, Rafael
    Zhang, Lijuan
    Yin, Ling
    Magaia, Naercio
    de Albuquerque, Victor Hugo C.
    APPLIED SOFT COMPUTING, 2022, 123
  • [39] Exploring COVID-19 Trends in Mexico during the Winter Season with Explainable Artificial Intelligence (XAI)
    Guzman-Ponce, Angelica
    Valdovinos-Rosas, Rosa Maria
    Gonzalez-Ruiz, Jacobo Leonardo
    Francisco-Valencia, Ivan
    Marcial-Romero, J. Raymundo
    IEEE LATIN AMERICA TRANSACTIONS, 2024, 22 (07) : 539 - 547
  • [40] Quantum Inspired Differential Evolution with Explainable Artificial Intelligence-Based COVID-19 Detection
    Basahel A.M.
    Yamin M.
    Computer Systems Science and Engineering, 2023, 46 (01): : 209 - 224