Anatomic Pathology of Hepatocellular Carcinoma Histopathology Using Classic and New Diagnostic Tools

被引：12
|
作者：
Pittman, Meredith E. [1 ]
Brunt, Elizabeth M. [2 ]
机构：
[1] Johns Hopkins Med Inst, Dept Pathol, Baltimore, MD 21231 USA
[2] Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63110 USA
来源：
CLINICS IN LIVER DISEASE | 2015年 / 19卷 / 02期
关键词：
Hepatocellular carcinoma; Liver biopsy; Dysplastic nodule; lmmunohistochemistry; Glypican-3; Glutamine synthetase; Arginase-1; Biphenotypic; GLYPICAN-3; EXPRESSION; DYSPLASTIC NODULES; PRENEOPLASTIC LESIONS; GLUTAMINE-SYNTHETASE; KERATIN; 19; LIVER; MARKER; TUMORS; DISTINCTION; HEPATOCYTE;
D O I：
10.1016/j.cld.2015.01.003
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Hepatocellular carcinoma can be diagnosed on a needle biopsy of the liver; however, uncertainty may arise because of the inherent complexity of liver histology. This article aims to provide practicing pathologists with tools for the approach to mass-directed liver biopsies clinically concerning for hepatocellular carcinoma. The examination of routine hematoxylin-eosin stains and the use of ancillary histochemical and immunohistochemical stains are discussed. Sections reviewing liver carcinoma with biphenotypic differentiation and the challenge of dysplastic nodules are included.
引用
收藏
页码：239 / +
页数：22
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