Anatomic Pathology of Hepatocellular Carcinoma Histopathology Using Classic and New Diagnostic Tools

被引：12

作者：

Pittman, Meredith E. ^{[1
]}

Brunt, Elizabeth M. ^{[2
]}

机构：

[1] Johns Hopkins Med Inst, Dept Pathol, Baltimore, MD 21231 USA

[2] Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63110 USA

来源：

CLINICS IN LIVER DISEASE | 2015年 / 19卷 / 02期

关键词：

Hepatocellular carcinoma; Liver biopsy; Dysplastic nodule; lmmunohistochemistry; Glypican-3; Glutamine synthetase; Arginase-1; Biphenotypic; GLYPICAN-3; EXPRESSION; DYSPLASTIC NODULES; PRENEOPLASTIC LESIONS; GLUTAMINE-SYNTHETASE; KERATIN; 19; LIVER; MARKER; TUMORS; DISTINCTION; HEPATOCYTE;

D O I：

10.1016/j.cld.2015.01.003

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Hepatocellular carcinoma can be diagnosed on a needle biopsy of the liver; however, uncertainty may arise because of the inherent complexity of liver histology. This article aims to provide practicing pathologists with tools for the approach to mass-directed liver biopsies clinically concerning for hepatocellular carcinoma. The examination of routine hematoxylin-eosin stains and the use of ancillary histochemical and immunohistochemical stains are discussed. Sections reviewing liver carcinoma with biphenotypic differentiation and the challenge of dysplastic nodules are included.

引用

页码：239 / +

页数：22

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