Anatomic Pathology of Hepatocellular Carcinoma Histopathology Using Classic and New Diagnostic Tools

被引：12

作者：

Pittman, Meredith E. ^{[1
]}

Brunt, Elizabeth M. ^{[2
]}

机构：

[1] Johns Hopkins Med Inst, Dept Pathol, Baltimore, MD 21231 USA

[2] Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63110 USA

来源：

CLINICS IN LIVER DISEASE | 2015年 / 19卷 / 02期

关键词：

Hepatocellular carcinoma; Liver biopsy; Dysplastic nodule; lmmunohistochemistry; Glypican-3; Glutamine synthetase; Arginase-1; Biphenotypic; GLYPICAN-3; EXPRESSION; DYSPLASTIC NODULES; PRENEOPLASTIC LESIONS; GLUTAMINE-SYNTHETASE; KERATIN; 19; LIVER; MARKER; TUMORS; DISTINCTION; HEPATOCYTE;

D O I：

10.1016/j.cld.2015.01.003

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Hepatocellular carcinoma can be diagnosed on a needle biopsy of the liver; however, uncertainty may arise because of the inherent complexity of liver histology. This article aims to provide practicing pathologists with tools for the approach to mass-directed liver biopsies clinically concerning for hepatocellular carcinoma. The examination of routine hematoxylin-eosin stains and the use of ancillary histochemical and immunohistochemical stains are discussed. Sections reviewing liver carcinoma with biphenotypic differentiation and the challenge of dysplastic nodules are included.

引用

页码：239 / +

页数：22

共 50 条

[21] Differential diagnostic between hepatocellular carcinoma and hepatoid carcinoma with bone metastasis revelation: What tools can be used?
Neyrand, Sophie
Bringuier, Pierre-Paul
Benzerdjeb, Nazim
Hervieu, Valerie
Fenouil, Tanguy
ANNALES DE PATHOLOGIE, 2023, 43 (05) : 407 - 411
[22] Synchronous association of hepatocellular carcinoma and cystic echinococcosis with unusual pathology: report on diagnostic and pathological variability
Suresh, Sushrutha Chikkanayakanahalli
Swamy, Nagesh N.
Shah, Pritik A.
Babu, Raghavendra
BMJ CASE REPORTS, 2021, 14 (12)
[23] Hepatocellular Carcinoma, Fibrolamellar Variant: Diagnostic Pathologic Criteria and Molecular Pathology Update. A Primer
Sergi, Consolato M.
DIAGNOSTICS, 2016, 6 (01):
[24] Circulating Long and Circular Noncoding RNA as Non-Invasive Diagnostic Tools of Hepatocellular Carcinoma
Sukowati, Caecilia H. C.
Cabral, Loraine Kay D.
Tiribelli, Claudio
Pascut, Devis
BIOMEDICINES, 2021, 9 (01) : 1 - 21
[25] Circulating Cell-Free DNA and DNA Integrity as Molecular Diagnostic Tools in Hepatocellular Carcinoma
Elzehery, Rasha
Effat, Narmin
El Farahaty, Reham
Farag, Raghda Elsayed
Abo-Hashem, Ekbal M.
Elhelaly, Rania
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2022, 158 (02) : 254 - 262
[26] Early diagnostic potential for hepatocellular carcinoma using the SELDI ProteinChip system
Kanmura, Shuji
Uto, Hirofumi
Kusumoto, Kazunori
Ishida, Yoichi
Hasuike, Satoru
Nagata, Kenji
Hayashi, Katsuhiro
Ido, Akio
Stuver, Sherri Oliver
Tsubouchi, Hirohito
HEPATOLOGY, 2007, 45 (04) : 948 - 956
[27] Construction of diagnostic models for the progression of hepatocellular carcinoma using machine learning
Jiang, Xin
Zhou, Ruilong
Jiang, Fengle
Yan, Yanan
Zhang, Zheting
Wang, Jianmin
FRONTIERS IN ONCOLOGY, 2024, 14
[28] IMMUNOSCORE CLASSIFICATION FROM HEPATOCELLULAR CARCINOMA HISTOPATHOLOGY IMAGES USING DEEP LEARNING: A PRELIMINARY STUDY
Chen, Qiaofeng
Gu, Yunquan
Wang, Ruixuan
Xiao, Han
Peng, Sui
Kuang, Ming
GUT, 2020, 69 : A78 - A79
[29] Nuclei detection in hepatocellular carcinoma and dysplastic liver nodules in histopathology images using bootstrap regression
Kalinathan, Lekshmi
Kathavarayan, Ruba Soundar
Kanmani, Madheswari
Dinakaran, Nagendram
HISTOLOGY AND HISTOPATHOLOGY, 2020, 35 (10) : 1115 - 1123
[30] Circular RNAs and Hepatocellular Carcinoma: New Epigenetic Players With Diagnostic and Prognostic Roles
Aishanjiang, Kedeerya
Wei, Xin-dong
Fu, Yi
Lin, Xinjie
Ma, Yujie
Le, Jiamei
Han, Qiuqin
Wang, Xuan
Kong, Xiaoni
Gu, Jinyang
Wu, Hailong
FRONTIERS IN ONCOLOGY, 2021, 11

← 1 2 3 4 5 →