Reactivities of piperazine-2,5-diones in radical bromination reactions

被引：5
|
作者：
Chai, CLL [1 ]
Hockless, DCR [1 ]
King, AR [1 ]
机构：
[1] AUSTRALIAN NATL UNIV,RES SCH CHEM,CANBERRA,ACT 0200,AUSTRALIA
来源：
AUSTRALIAN JOURNAL OF CHEMISTRY | 1996年 / 49卷 / 11期
关键词：
D O I：
10.1071/CH9961229
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The reactivities of various N,N'-diacetylated piperazine-2,5-diones towards radical bromination reactions are reported. The studies show that glycyl centres of piperazine-2,5-diones are more reactive towards radical bromination reactions compared to alpha-substituted amino acid centres. In addition, large differences in reactivities were observed for the cis and trans isomers of N,Nl-diacetylated alanine anhydride. Single-crystal structure determination of each isomer revealed that conformational effects may account for the difference in chemical reactivity.
引用
收藏
页码：1229 / 1233
页数：5
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