Reactivities of piperazine-2,5-diones in radical bromination reactions

被引：5

作者：

Chai, CLL ^{[1
]}

Hockless, DCR ^{[1
]}

King, AR ^{[1
]}

机构：

[1] AUSTRALIAN NATL UNIV,RES SCH CHEM,CANBERRA,ACT 0200,AUSTRALIA

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 1996年 / 49卷 / 11期

关键词：

D O I：

10.1071/CH9961229

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reactivities of various N,N'-diacetylated piperazine-2,5-diones towards radical bromination reactions are reported. The studies show that glycyl centres of piperazine-2,5-diones are more reactive towards radical bromination reactions compared to alpha-substituted amino acid centres. In addition, large differences in reactivities were observed for the cis and trans isomers of N,Nl-diacetylated alanine anhydride. Single-crystal structure determination of each isomer revealed that conformational effects may account for the difference in chemical reactivity.

引用

页码：1229 / 1233

页数：5

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