Depsitinuside: a new depside galactoside from an endophytic fungus isolated from Viburnum tinus

被引：2

作者：

Nazir, Mamona ^{[1
]}

Sultan, Misbah ^{[1
]}

Riaz, Naheed ^{[1
]}

Hafeez, Maria ^{[1
]}

Hussain, Hidayat ^{[2
]}

Ahmed, Ishtiaq ^{[2
]}

Schulz, Barbara ^{[3
]}

Draeger, Siegfried ^{[3
]}

Jabbar, Abdul ^{[1
]}

Krohn, Karsten ^{[2
]}

Ashraf, Muhammad ^{[4
]}

Saleem, Muhammad ^{[1
]}

机构：

[1] Islamia Univ Bahawalpur, Dept Chem, Bahawalpur 63100, Pakistan

[2] Univ Paderborn, Dept Chem, D-33098 Paderborn, Germany

[3] Tech Univ Carolo Wilhelmina Braunschweig, Inst Microbiol, D-31806 Braunschweig, Germany

[4] Islamia Univ Bahawalpur, Fac Pharm & Alternat Med, Dept Pharm, Bahawalpur 63100, Pakistan

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2011年 / 13卷 / 11期

关键词：

Viburnum tinus; endophytic fungus; depside; steroids; enzyme inhibition; SECONDARY METABOLITES; NATURAL-PRODUCTS; MICROORGANISMS; DIVERSITY;

D O I：

10.1080/10286020.2011.606811

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Chromatographic purification of the extract of an endophytic fungal culture yielded depsitinuside (1), a new phenolic ester together with ergosterol (2) and (22E,24S)-24-methyl-5-alpha-cholesta-7,22-diene-3 beta,5,6 beta-triol (3).The structure of 1 was elucidated based on 1D, 2D NMR spectroscopy and high-resolution mass spectrometry, whereas the known compounds (2 and 3) were identified by 1 H NMR, mass spectrometry, and in comparison with the literature values. Compound 1 was evaluated for its enzyme inhibitory potential against acetylcholinesterase, butyrylcholinesterase and lipoxygenase, and was found inactive (10%-40% inhibition at a concentration of 2 mg/ml).

引用

页码：1056 / 1060

页数：5

共 50 条

[31] Antimicrobial perylenequinones isolated from the endophytic fungus Alternaria alstroemeriae
Li, Yong-Fu
Yue, Fang
Wan, Xu-Ri
Li, Chang
Sun, Yi
Pei, Yue-Hu
PHYTOCHEMISTRY LETTERS, 2025, 65 : 64 - 67
[32] Phytosterols isolated from endophytic fungus Colletotrichum gloeosporioides (Melanconiaceae)
Carvalho, Josiwander Miranda
Olimpio da Paixao, Luanna Karyna
Dolabela, Maria Fani
Barbosa Marinho, Patricia Santana
do Rosario Marinho, Andrey Moacir
ACTA AMAZONICA, 2016, 46 (01) : 69 - 72
[33] In vitro cytotoxicity of an endophytic fungus isolated from Nothapodytes foetida
Rehman, Suriya
Shawl, Abdul Sami
Sultana, Sarvat
Kouri, Arnardeep
Riyaz-Ul-Hassan, Syed
Qazi, Ghulam Nabi
ANNALS OF MICROBIOLOGY, 2009, 59 (01) : 157 - 161
[34] Polyhydroxylated macrolide isolated from the endophytic fungus Pestalotiopsis mangiferae
Ortega, Humberto. E.
Shen, Young Yongchun
TenDyke, Karen
Rios, Nivia
Cubilla-Rios, Luis
TETRAHEDRON LETTERS, 2014, 55 (16) : 2642 - 2645
[35] New oblongolides isolated from the endophytic fungus Phomopsis sp from Melilotus dentata from the shores of the Baltic Sea
Dai, JQ
Krohn, K
Gehle, D
Kock, I
Flörke, U
Aust, HJ
Draeger, S
Schulz, B
Rheinheimer, J
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2005, 2005 (18) : 4009 - 4016
[36] Sesquiterpenes Isolated from Aspergillus fumigatus, an Endophytic Fungus from Ligusticum wallichii
Li, Xiao-Hua
Hu, Han-Wen
Tan, Lu
Wu, Wen-Lin
Cao, Zhi-Xing
Gu, Yu-Cheng
Deng, Yun
Guo, Da-le
NATURAL PRODUCT COMMUNICATIONS, 2018, 13 (11) : 1419 - 1420
[37] Two new metabolites from the endophytic fungus Xylaria sp isolated from the medicinal plant Curcuma xanthorrhiza
Hammerschmidt, Lena
Ola, Antonius
Mueller, Werner E. G.
Lin, WenHan
Mandi, Attila
Kurtan, Tibor
Proksch, Peter
Aly, Amal H.
TETRAHEDRON LETTERS, 2015, 56 (10) : 1193 - 1197
[38] New polyketides from the endophytic fungus Pestalotiopsis sp isolated from the Chinese mangrove plant Rhizophora mucronata
Xu, J.
Kjer, J.
Sendker, J.
Wray, V
Guan, H.
Lin, W.
Wu, J.
Proksch, P.
PLANTA MEDICA, 2009, 75 (09) : 1074 - 1074
[39] New polyketides from the endophytic fungus Corynespora cassiicola isolated from the Chinese mangrove plant Laguncularia racemosa
Ebrahim, W.
Wray, V
Pretsch, A.
Proksch, P.
Debbab, A.
PLANTA MEDICA, 2010, 76 (12) : 1316 - 1316
[40] Bioactive secondary metabolites from new endophytic fungus Curvularia. sp isolated from Rauwolfia macrophylla
Kaaniche, Fatma
Hamed, Abdelaaty
Abdel-Razek, Ahmed S.
Wibberg, Daniel
Abdissa, Negera
El Euch, Imene Zendah
Allouche, Noureddine
Mellouli, Lotfi
Shaaban, Mohamed
Sewald, Nobert
PLOS ONE, 2019, 14 (06):

← 1 2 3 4 5 →