Can Gram-Negative Bacteria Develop Resistance to Antimicrobial Blue Light Treatment?

被引：14
|
作者：
Rapacka-Zdonczyk, Aleksandra [1 ]
Wozniak, Agata [2 ,3 ]
Kruszewska, Beata [1 ,2 ,3 ]
Waleron, Krzysztof [1 ]
Grinholc, Mariusz [2 ,3 ]
机构：
[1] Med Univ Gdansk, Fac Pharm, Dept Pharmaceut Microbiol, Hallera 107, PL-80416 Gdansk, Poland
[2] Univ Gdansk, Intercollegiate Fac Biotechnol, Lab Photobiol & Mol Diagnost, Abrahama 58, PL-80307 Gdansk, Poland
[3] Med Univ Gdansk, Abrahama 58, PL-80307 Gdansk, Poland
来源：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2021年 / 22卷 / 21期
关键词：
antimicrobial blue light; resistance; tolerance; Escherichia coli; Klebsiella pneumoniae; Pseudomonas aeruginosa; 405 NM LIGHT; PSEUDOMONAS-AERUGINOSA; STAPHYLOCOCCUS-AUREUS; IN-VITRO; SOLVENT TOLERANCE; ACID TOLERANCE; ERROR-PRONE; EFFLUX; INACTIVATION; PHOTOINACTIVATION;
D O I：
10.3390/ijms222111579
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Antimicrobial blue light (aBL) treatment is considered low risk for the development of bacterial resistance and tolerance due to its multitarget mode of action. The aim of the current study was to demonstrate whether tolerance development occurs in Gram-negative bacteria. We evaluated the potential of tolerance/resistance development in Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa and demonstrated that representative Gram-negative bacteria may develop tolerance to aBL. The observed adaption was a stable feature. Assays involving E. coli K-12 tolC-, tolA-, umuD-, and recA-deficient mutants revealed some possible mechanisms for aBL tolerance development.
引用
收藏
页数：16
相关论文
共 50 条
  • [41] Quinolones sensitize gram-negative bacteria to antimicrobial peptides
    Campos, Miguel A.
    Morey, Pau
    Bengoechea, Jose A.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2006, 50 (07) : 2361 - 2367
  • [42] Antimicrobial Blue Light Inactivation of Gram-Negative Pathogens in Biofilms: In Vitro and In Vivo Studies
    Wang, Yucheng
    Wu, Ximing
    Chen, Jia
    Amin, Rehab
    Lu, Min
    Bhayana, Brijesh
    Zhao, Jie
    Murray, Clinton K.
    Hamblin, Michael R.
    Hooper, David C.
    Dai, Tianhong
    JOURNAL OF INFECTIOUS DISEASES, 2016, 213 (09): : 1380 - 1387
  • [43] Seafood as a Reservoir of Gram-negative Bacteria Carrying Integrons and Antimicrobial Resistance Genes in Japan
    Ashraf M.Ahmed
    Akito Maruyama
    Hazim O.Khalifa
    Toshi Shimamoto
    Tadashi Shimamoto
    Biomedical and Environmental Sciences, 2015, 28 (12) : 924 - 927
  • [44] Predicting and preventing antimicrobial resistance utilizing pharmacodynamics: part II Gram-negative bacteria
    Abdelraouf, Kamilia
    Linder, Kristin E.
    Nailor, Michael D.
    Nicolau, David P.
    EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 2017, 13 (07) : 705 - 714
  • [45] Seafood as a Reservoir of Gram-negative Bacteria Carrying Integrons and Antimicrobial Resistance Genes in Japan
    Ahmed, Ashraf M.
    Maruyama, Akito
    Khalifa, Hazim O.
    Shimamoto, Toshi
    Shimamoto, Tadashi
    BIOMEDICAL AND ENVIRONMENTAL SCIENCES, 2015, 28 (12) : 924 - 927
  • [46] Drivers of virulence and antimicrobial resistance in Gram-negative bacteria in different settings: A genomic perspective
    Singh, Anuradha
    Rani, Pittu Sandhya
    Bandsode, Viraj
    Nyambero, Mahanga
    Qumar, Shamsul
    Ahmed, Niyaz
    INFECTION GENETICS AND EVOLUTION, 2024, 124
  • [47] Antimicrobial resistance among non-fermenting Gram-negative bacteria in Saudi Arabia
    Memish, Ziad A.
    Shibl, Atef M.
    Kambal, Abdelmageed M.
    Ohaly, Yazid A.
    Ishaq, Abdulrahman
    Livermore, David M.
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2012, 67 (07) : 1701 - 1705
  • [48] Prevalence of Antimicrobial Resistance Genes and Integrons in Commensal Gram-Negative Bacteria in a College Community
    Rubin, Julia
    Mussio, Kaitlyn
    Xu, Yuqi
    Suh, Joy
    Riley, Lee W.
    MICROBIAL DRUG RESISTANCE, 2020, 26 (10) : 1227 - 1235
  • [49] Zoo animals as reservoirs of gram-negative bacteria harboring integrons and antimicrobial resistance genes
    Ahmed, Ashraf M.
    Motoi, Yusuke
    Sato, Maiko
    Maruyama, Makito
    Watanabe, Hitoshi
    Fukumoto, Yukio
    Shimamoto, Tadashi
    APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2007, 73 (20) : 6686 - 6690
  • [50] Performance of automated antimicrobial susceptibility testing for the detection of antimicrobial resistance in gram-negative bacteria: a NordicAST study
    Leegaard, Truls S.
    Justesen, Ulrik
    Matuschek, Erika G.
    Giske, Christian
    NordicAST Study Grp Automated AST
    APMIS, 2023, 131 (10) : 543 - 551
12345