A new anti-proliferative acylated flavonol glycoside from Fuzhuan brick-tea

被引：39

作者：

Tian, Yong-Zhen ^{[1
]}

Liu, Xiao ^{[1
]}

Liu, Wen ^{[2
]}

Wang, Wei-Yun ^{[2
]}

Long, Yan-Hua ^{[2
]}

Zhang, Liang ^{[1
]}

Xu, Yan ^{[1
]}

Bao, Guan-Hu ^{[1
]}

Wan, Xiao-Chun ^{[1
]}

Ling, Tie-Jun ^{[1
]}

机构：

[1] Anhui Agr Univ, State Key Lab Tea Plant Biol & Utilizat, Hefei, Peoples R China

[2] Anhui Agr Univ, Sch Life Sci, Hefei, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2016年 / 30卷 / 23期

关键词：

Fuzhuan brick-tea; dark tea; camellikaempferoside A; anti-proliferative activity; MCF-7; cells; MDA-MB-231; FERMENTED CAMELLIA-SINENSIS; MICROBIAL FERMENTATION; HUMAN HEALTH; CONSTITUENTS; CATECHINS; OLEIFERA;

D O I：

10.1080/14786419.2015.1136911

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Fuzhuan brick-tea (FBT) is unique for a fungal fermentation stage in its manufacture process and is classified in dark tea. A new acylated flavonol glycoside, kaempferol 3-O-[E-p-coumaroyl-(2)][-l-arabinopyranosyl-(13)][-l-rhamnopyranosyl(16)]--d-glucopyranoside, which was trivially named as camellikaempferoside A (1), was isolated from FBT along with camelliquercetiside C (2). Their structures were unambiguously elucidated by combination of spectroscopic and chemical methods. Compound 1 showed anti-proliferative activity against MCF-7 and MDA-MB-231 cells with IC50 values of 7.83 and 19.16M, respectively. [GRAPHICS] .

引用

页码：2637 / 2641

页数：5

共 50 条

[1] Antimicrobial activity of the indigenously microbial fermented Fuzhuan brick-tea
Mo, Haizhen
Zhang, Hao
Li, Yingqiu
Zhu, Yang
JOURNAL OF BIOTECHNOLOGY, 2008, 136 : S722 - S722
[2] Fungal community associated with fermentation and storage of Fuzhuan brick-tea
Xu, Aiqing
Wang, Yuanliang
Wen, Jieyu
Liu, Ping
Liu, Ziyin
Li, Zongjun
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2011, 146 (01) : 14 - 22
[3] A New Acylated Flavonol Glycoside from Chenopodium foliosum
Kokanova-Nedialkova, Zlatina
Kondeva-Burdina, Magdalena
Zheleva-Dimitrova, Dimitrina
Buecherl, Daniel
Nikolov, Stefan
Heilmann, Joerg
Nedialkov, Paraskev T.
RECORDS OF NATURAL PRODUCTS, 2014, 8 (04) : 401 - 406
[4] A new acylated flavonol glycoside from Derris triofoliata
Xu, Lu-Rong
Wu, Jun
Zhang, Si
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2006, 8 (1-2) : 9 - 13
[5] Electron beam irradiation on Fuzhuan brick-tea: Effects on sensory quality and chemical compositions
Zhang, Haiwei
Zhang, Yajuan
Chambers, Edgar
Dai, Qianying
RADIATION PHYSICS AND CHEMISTRY, 2020, 170 (170)
[6] A New Norisoprenoid and Other Compounds from Fuzhuan Brick Tea
Luo, Zhen-Mei
Ling, Tie-Jun
Li, Li-Xiang
Zhang, Zheng-Zhu
Zhu, Hong-Tao
Zhang, Ying-Jun
Wan, Xiao-Chun
MOLECULES, 2012, 17 (03) : 3539 - 3546
[7] NEW ACYLATED FLAVONOL GLYCOSIDE FROM GNAPHALIUM-ULIGINOSUM
KONOPLEVA, MM
SMIRNOVA, LP
GLYZIN, VI
SHELYUTO, VL
KHIMIYA PRIRODNYKH SOEDINENII, 1979, (03): : 311 - 315
[8] A new acylated flavonol glycoside from the leaves of Eriobotrya japonica
Kawahara, N
Satake, M
Goda, Y
CHEMICAL & PHARMACEUTICAL BULLETIN, 2002, 50 (12) : 1619 - 1620
[9] Analysis of characteristic aroma of fungal fermented Fuzhuan brick-tea by gas chromatography/mass spectrophotometry
Xu, Xiangqun
Mo, Haizhen
Yan, Mingchao
Zhu, Yang
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2007, 87 (08) : 1502 - 1504
[10] Effect of Fuzhuan brick-tea addition on the quality and antioxidant activity of skimmed set-type yoghurt
Liu, Dong
INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY, 2018, 71 : 22 - 33

← 1 2 3 4 5 →