Cytotoxic activities of Colombian plant extracts on Chinese hamster lung fibroblasts

被引：0
|
作者：
deCerain, AL [2 ]
Pinzon, R
Calle, J
Marin, A
Monge, A
机构：
[1] UNIV NATL COLOMBIA, FAC SCI, DEPT PHARM, SANTA FE DE BOGOTA, COLOMBIA
[2] UNIV NAVARRA, CIFA, DEPT TOXICOL, E-31008 PAMPLONA, SPAIN
[3] UNIV NAVARRA, CIFA, DEPT ORGAN CHEM, E-31008 PAMPLONA, SPAIN
来源：
PHYTOTHERAPY RESEARCH | 1996年 / 10卷 / 05期
关键词：
Colombian plants; cytotoxicity; MTT; V79; Acnistus arborescens;
D O I：
10.1002/(SICI)1099-1573(199608)10:5<431::AID-PTR863>3.0.CO;2-M
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Fifty-one crude extracts from 31 Colombian plants used in traditional medicine have been screened for cytotoxicity in a MTT assay with V79 cells. Eleven extracts (21%) were active, showing a survival percentage below 20% with respect to the controls, The most active were ethanol and dichloromethane extracts from Acnistus arborescens leaves. The IC50 values obtained (6 and 11 mu g/mL) encourage a more in depth investigation.
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页码：431 / 432
页数：2
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