Cytotoxic activities of Colombian plant extracts on Chinese hamster lung fibroblasts

被引：0

作者：

deCerain, AL ^{[2
]}

Pinzon, R

Calle, J

Marin, A

Monge, A

机构：

[1] UNIV NATL COLOMBIA, FAC SCI, DEPT PHARM, SANTA FE DE BOGOTA, COLOMBIA

[2] UNIV NAVARRA, CIFA, DEPT TOXICOL, E-31008 PAMPLONA, SPAIN

[3] UNIV NAVARRA, CIFA, DEPT ORGAN CHEM, E-31008 PAMPLONA, SPAIN

来源：

PHYTOTHERAPY RESEARCH | 1996年 / 10卷 / 05期

关键词：

Colombian plants; cytotoxicity; MTT; V79; Acnistus arborescens;

D O I：

10.1002/(SICI)1099-1573(199608)10:5<431::AID-PTR863>3.0.CO;2-M

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Fifty-one crude extracts from 31 Colombian plants used in traditional medicine have been screened for cytotoxicity in a MTT assay with V79 cells. Eleven extracts (21%) were active, showing a survival percentage below 20% with respect to the controls, The most active were ethanol and dichloromethane extracts from Acnistus arborescens leaves. The IC50 values obtained (6 and 11 mu g/mL) encourage a more in depth investigation.

引用

页码：431 / 432

页数：2

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