Cytotoxic activities of Colombian plant extracts on Chinese hamster lung fibroblasts

被引：0
|
作者：
deCerain, AL [2 ]
Pinzon, R
Calle, J
Marin, A
Monge, A
机构：
[1] UNIV NATL COLOMBIA, FAC SCI, DEPT PHARM, SANTA FE DE BOGOTA, COLOMBIA
[2] UNIV NAVARRA, CIFA, DEPT TOXICOL, E-31008 PAMPLONA, SPAIN
[3] UNIV NAVARRA, CIFA, DEPT ORGAN CHEM, E-31008 PAMPLONA, SPAIN
来源：
PHYTOTHERAPY RESEARCH | 1996年 / 10卷 / 05期
关键词：
Colombian plants; cytotoxicity; MTT; V79; Acnistus arborescens;
D O I：
10.1002/(SICI)1099-1573(199608)10:5<431::AID-PTR863>3.0.CO;2-M
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Fifty-one crude extracts from 31 Colombian plants used in traditional medicine have been screened for cytotoxicity in a MTT assay with V79 cells. Eleven extracts (21%) were active, showing a survival percentage below 20% with respect to the controls, The most active were ethanol and dichloromethane extracts from Acnistus arborescens leaves. The IC50 values obtained (6 and 11 mu g/mL) encourage a more in depth investigation.
引用
收藏
页码：431 / 432
页数：2
相关论文
共 50 条
  • [11] Trypanocidal and cytotoxic activity of extracts of Colombian plants
    Valencia, Lorena
    Lorena Munoz, Diana
    Maria Robledo, Sara
    Echeverri, Fernando
    Jaime Arango, Gabriel
    Dario Velez, Ivan
    Triana, Omar
    BIOMEDICA, 2011, 31 (04): : 552 - 559
  • [12] Antileishmanial and cytotoxic activities of four Andean plant extracts from Colombia
    Cardona-G, Wilson
    Robledo, Sara
    Alzate, Fernando
    Yepes, Andres F.
    Hernandez, Cristian
    Velez, Ivan Dario
    Calderon, Juan Carlos
    Tabares, Isabel Vasquez
    VETERINARY WORLD, 2020, 13 (10) : 2178 - 2182
  • [13] HYPOXANTHINE TRANSPORT BY CHINESE-HAMSTER LUNG FIBROBLASTS - KINETICS AND INHIBITION BY NUCLEOSIDES
    SLAUGHTER, RS
    BARNES, EM
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1979, 197 (01) : 349 - 355
  • [14] Chromosome aberration test of diphenylchloroarsine (DA) in Chinese hamster lung fibroblasts (CHL)
    Gao, C
    Wang, HF
    Zhang, J
    Li, YJ
    PROGRESS IN SAFETY SCIENCE AND TECHNOLOGY, VOL V, PTS A AND B, 2005, 5 : 2154 - 2158
  • [15] Chromosome Aberration Test of Chloroacetophenone (CN) in Chinese Hamster Lung Fibroblasts (CHL)
    Zhang Jing
    Wang Huifang
    Gao Chuan
    PROGRESS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY, VOL III: PROCEEDINGS OF THE 2011 INTERNATIONAL SYMPOSIUM ON ENVIRONMENTAL SCIENCE AND TECHNOLOGY, 2011, : 93 - 98
  • [16] THYMIDINE TRANSPORT IN CHINESE-HAMSTER LUNG FIBROBLASTS IS COMPETITIVELY INHIBITED BY HYPOXANTHINE
    SLAUGHTER, RS
    BARNES, EM
    FEDERATION PROCEEDINGS, 1980, 39 (06) : 2158 - 2158
  • [17] Antiprotozoal and cytotoxic activities in vitro of Colombian Annonaceae
    Osorio, Edison
    Arango, Gabriel Jaime
    Jimenez, Nora
    Alzate, Fernando
    Ruiz, Grace
    Gutierrez, David
    Paco, Marco Antonio
    Gimenez, Alberto
    Robledo, Sara
    JOURNAL OF ETHNOPHARMACOLOGY, 2007, 111 (03) : 630 - 635
  • [18] NUCLEOTIDE ECTOENZYME ACTIVITIES OF HUMAN AND CHINESE-HAMSTER FIBROBLASTS IN TISSUE-CULTURE
    BOYLE, JM
    HEY, Y
    FOX, M
    BIOCHEMICAL GENETICS, 1989, 27 (11-12) : 655 - 671
  • [19] LYSOSOMES IN CHINESE HAMSTER FIBROBLASTS IN CULTURE
    MUNRO, TR
    DINGLE, JT
    DANIEL, MR
    EXPERIMENTAL CELL RESEARCH, 1964, 35 (03) : 515 - +
  • [20] Internalization and Limited Processing of Basic Fibroblast Growth Factor on Chinese Hamster Lung Fibroblasts
    Moenner, Michel
    Gannoun-Zaki, Leila
    Badet, Josette
    Barritault, Denis
    GROWTH FACTORS, 1989, 1 (02) : 115 - 123
12345