Flow injection amperometric detection of 2′-deoxyguanosine at a ruthenium oxide hexacyanoferrate modified electrode

被引：22

作者：

Paixao, Thiago R. L. C. ^{[1
]}

Garcia, Camila C. M. ^{[1
]}

Medeiros, Marisa H. G. ^{[1
]}

Bertotti, Mauro ^{[1
]}

机构：

[1] Univ Sao Paulo, Inst Quim, BR-05508900 Sao Paulo, SP, Brazil

来源：

ANALYTICAL CHEMISTRY | 2007年 / 79卷 / 14期

关键词：

D O I：

10.1021/ac070490e

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A ruthenium oxide hexacyanoferrate (RuOHCF) modified electrode was developed. Hydrodynamic voltammetry was employed to demonstrate the remarkable electrocatalytic activity toward the oxidation of 2 '-deoxyguanosine. The RuOHCF modified electrode was used as amperometric detector for 2 '-deoxyguanosine determination in a FIA apparatus. The influence of various experimental conditions was explored for optimum analytical performance, and at these experimental conditions, the method exhibited a linear response range to 2 '-deoxyguanosine extending from 3.8 to 252 mu mol L-1 with detection limit of 94 nmol L-1. Applications in DNA samples were examined, and the results for determination of 2 '-deoxyguanosine were in good agreement with those obtained by HPLC analysis. Studies on the kinetics of the in vitro consumption of 2 '-deoxyguanosine by acetaldehyde were also performed.

引用

页码：5392 / 5398

页数：7

共 50 条

[41] Amperometric detection of hydrazine by cyclic voltammetry and flow injection analysis using ruthenium modified glassy carbon electrodes
Pinter, Jill S.
Brown, Kenneth L.
DeYoung, Paul A.
Peaslee, Graham F.
TALANTA, 2007, 71 (03) : 1219 - 1225
[42] ENZYME ELECTRODE FOR GLUCOSE BASED ON AMPEROMETRIC DETECTION OF HEXACYANOFERRATE II
MAHENC, J
AUSSARESSES, H
COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE C, 1979, 289 (14): : 357 - 359
[43] Electrochemical study and flow-injection amperometric detection of trace NO2 at CuPtCl6 chemically modified electrode
Pei, JH
Li, XY
TALANTA, 2000, 51 (06) : 1107 - 1115
[44] Ruthenium oxide modified nickel electrode for ascorbic acid detection
Lee, Yuan-Gee
Liao, Bo-Xuan
Weng, Yu-Ching
CHEMOSPHERE, 2017, 173 : 512 - 519
[45] Glucose determination in blood samples using flow injection analysis and an amperometric biosensor based on glucose oxidase immobilized on hexacyanoferrate modified nickel electrode
Milardovic, S
Kruhak, I
Ivekovic, D
Rumenjak, V
Tkalcec, M
Grabaric, BS
ANALYTICA CHIMICA ACTA, 1997, 350 (1-2) : 91 - 96
[46] Amperometric Detection of Nitrite Using Chitosan Protected Nickel Hexacyanoferrate Nanoparticles Modified Glassy Carbon Electrode
Sophia, S. Jancy
Devi, S.
Pandian, K.
ASIAN JOURNAL OF CHEMISTRY, 2013, 25 : S366 - S368
[47] FLOW-INJECTION AMPEROMETRIC DETECTION OF HYDRAZINE BY ELECTROCATALYTIC OXIDATION AT A PRUSSIAN BLUE FILM-MODIFIED ELECTRODE
HOU, WY
WANG, E
ANALYTICA CHIMICA ACTA, 1992, 257 (02) : 275 - 280
[48] AMPEROMETRIC DETECTION OF AMINES AND AMINO-ACIDS IN FLOW-INJECTION SYSTEMS WITH A NICKEL-OXIDE ELECTRODE
HUI, BS
HUBER, CO
ANALYTICA CHIMICA ACTA, 1982, 134 (JAN) : 211 - 218
[49] Flow injection amperometric detection at enzyme-modified gold nanoelectrodes
Delvaux, M
Demoustier-Champagne, S
Walcarius, A
ELECTROANALYSIS, 2004, 16 (03) : 190 - 198
[50] Studies on the Electrocatalytic Reduction of Hydrogen Peroxide on a Glassy Carbon Electrode Modified With a Ruthenium Oxide Hexacyanoferrate Film
Pena, Roselyn C.
Gamboa, Juan C. M.
Bertotti, Mauro
Paixao, Thiago R. L. C.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, 2011, 6 (02): : 394 - 403

← 1 2 3 4 5 →