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Catalyst Free Indirect Friedlander Synthesis of Substituted Quinolines from Alcohols in PEG-400
被引:10
|作者:
Wu, Fang-Wen
[2
]
Hou, Rei-Sheu
[1
]
Wang, Huey-Min
[1
]
Kang, Iou-Jiun
[3
]
Chen, Ling-Ching
[2
]
机构:
[1] Chung Hwa Coll Med Technol, Tainan 717, Taiwan
[2] Kaohsiung Med Univ, Grad Inst Pharmaceut Sci, Coll Pharm, Kaohsiung 807, Taiwan
[3] Yung Shin Pharmaceut, Dept Res & Dev, Taichung, Taiwan
关键词:
Friedlander annulation;
Quinoxaline;
Poly(ethylene glycol);
POLY(ETHYLENE GLYCOL) PEG;
ONE-STEP SYNTHESIS;
2-AMINOBENZYL ALCOHOL;
RECYCLABLE REACTION;
IONIC LIQUIDS;
SOLVENT;
DERIVATIVES;
EFFICIENT;
KETONES;
POLYMERS;
D O I:
10.1002/jccs.201100404
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
The synthesis of substituted quinolines can be easily and greenly accomplished by the direct reaction between the corresponding aminoalcohol and ketone using PEG-400 as reaction medium in the presence of a base, without any transition-metal catalyst.
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页码:535 / 539
页数:5
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