Catalyst Free Indirect Friedlander Synthesis of Substituted Quinolines from Alcohols in PEG-400

被引：10
|
作者：
Wu, Fang-Wen [2 ]
Hou, Rei-Sheu [1 ]
Wang, Huey-Min [1 ]
Kang, Iou-Jiun [3 ]
Chen, Ling-Ching [2 ]
机构：
[1] Chung Hwa Coll Med Technol, Tainan 717, Taiwan
[2] Kaohsiung Med Univ, Grad Inst Pharmaceut Sci, Coll Pharm, Kaohsiung 807, Taiwan
[3] Yung Shin Pharmaceut, Dept Res & Dev, Taichung, Taiwan
来源：
JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2012年 / 59卷 / 04期
关键词：
Friedlander annulation; Quinoxaline; Poly(ethylene glycol); POLY(ETHYLENE GLYCOL) PEG; ONE-STEP SYNTHESIS; 2-AMINOBENZYL ALCOHOL; RECYCLABLE REACTION; IONIC LIQUIDS; SOLVENT; DERIVATIVES; EFFICIENT; KETONES; POLYMERS;
D O I：
10.1002/jccs.201100404
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The synthesis of substituted quinolines can be easily and greenly accomplished by the direct reaction between the corresponding aminoalcohol and ketone using PEG-400 as reaction medium in the presence of a base, without any transition-metal catalyst.
引用
收藏
页码：535 / 539
页数：5
相关论文
共 50 条
  • [31] Convenient synthesis of novel heteroatom-substituted quinolines via Friedlander annulation using phosphotungstic acid as a reusable catalyst
    Chen, Meng-Meng
    Zhang, Min
    Xie, Feng
    Wang, Xiao-Ting
    MONATSHEFTE FUR CHEMIE, 2015, 146 (04): : 663 - 671
  • [32] Polyethylene glycol (PEG-400) as an efficient and recyclable reaction medium for one-pot synthesis of polysubstituted pyrroles under catalyst-free conditions
    Nagarapu, Lingaiah
    Mallepalli, Raghu
    Yeramanchi, Lingappa
    Bantu, Rajashaker
    TETRAHEDRON LETTERS, 2011, 52 (26) : 3401 - 3404
  • [33] Synthesis of novel chromeno[1,6]naphthyridine derivatives in PEG-400 via catalyst-free, one-pot, and multicomponent reactions
    Asilpour, Fatemeh
    Saberi, Dariush
    Hasaninejad, Alireza
    NEW JOURNAL OF CHEMISTRY, 2023, 48 (01) : 237 - 243
  • [34] Synthesis of Substituted Quinolines Using the Friedlander Reaction Under Microwave Irradiation Techniques
    Mehta, Prajkta
    Jadhav, Sarika
    Gadekar, Suchita
    Sapkal, Suryakant
    Gawai, Jaishree
    LETTERS IN ORGANIC CHEMISTRY, 2025,
  • [35] Molecular iodine:: a highly efficient catalyst in the synthesis of quinolines via Friedlander annulation
    Wu, J
    Xia, HG
    Gao, K
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2006, 4 (01) : 126 - 129
  • [36] Synthesis of α1-oxindole-α-hydroxyphosphonates under catalyst-free conditions using polyethylene glycol (PEG-400) as an efficient and recyclable reaction medium
    Nagarapu, Lingaiah
    Mallepalli, Raghu
    Kumar, U. Nikhil
    Venkateswarlu, P.
    Bantu, Rajashaker
    Yeramanchi, Lingappa
    TETRAHEDRON LETTERS, 2012, 53 (14) : 1699 - 1700
  • [37] Water mediated synthesis of substituted Quinolines - A new green approach to the Friedlander annulation
    Selvam, Nagarajan Panneer
    Saravanan, Chandramathi
    Muralidharan, D.
    Perumal, Paramasivan T.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2006, 43 (05) : 1379 - 1382
  • [38] Silica supported phosphomolybdic acid: An efficient heterogeneous catalyst for Friedlander synthesis of quinolines
    Das, Biswanath
    Krishnaiah, Martha
    Laxminarayana, Keetha
    Nandankumar, Duddukuri
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2008, 56 (07) : 1049 - 1051
  • [39] Recyclable nanoparticulate copper mediated synthesis of naphthoxazinones in PEG-400: a green approach
    Kumar, Ajeet
    Saxena, Amit
    Dewan, Manika
    De, Arnab
    Mozumdar, Subho
    TETRAHEDRON LETTERS, 2011, 52 (38) : 4835 - 4839
  • [40] Hypervalent Iodine(III) Sulfonate Mediated Synthesis of Quinoxalines in Liquid PEG-400
    Lin, Pei-Ying
    Hou, Rei-Sheu
    Wang, Huey-Min
    Kang, Iou-Jiun
    Chen, Ling-Ching
    JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2009, 56 (04) : 683 - 687
12345