(±)-trans-2-[3-methoxy-4-(4-chlorophenyl thioethoxy)-5-cyanophenyl]-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran, a potent PAF-receptor antagonist

被引：2
|
作者：
Ram, B [1 ]
Balram, B [1 ]
Prakash, PKS [1 ]
机构：
[1] Osmania Univ, Dept Chem, Hyderabad 500007, Andhra Pradesh, India
来源：
TETRAHEDRON | 1999年 / 55卷 / 33期
关键词：
platelet-activating factor; 2,5-transdiaryltetrahydrofuran; acetovanillone;
D O I：
10.1016/S0040-4020(99)00544-X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of (+/-)-trans-2-[3-methoxy-4-(chlorophenylthioethoxyphenyl)-5-cyanophenyl]-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran from conmercially available acetovanillone and 3,4,5-trimethoxybenzaldehyde is described. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：10163 / 10172
页数：10
相关论文
共 50 条
  • [41] 5-(2-chlorophenyl)-3-(4-chlorophenyl)-1-phenyl-2-pyrazoline
    Guo, Huan-Mei
    Jian, Fang-Fang
    Zhao, Pu-Su
    Zhang, Yun-Chen
    Li, Yu-Feng
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 63 : O215 - O216
  • [42] 5-(4-chlorophenyl)-3-(4-nitrophenyl)-1-phenyl-2-pyrazoline
    Guo, Huan-Mei
    Jian, Fang-Fang
    Li, Yu-Feng
    Lin, Cui-Hua
    Wu, Qian
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 63 : O1814 - O1815
  • [43] C-13 NUCLEAR MAGNETIC-RESONANCE SPECTRA OF 5-(3,4,5-TRIMETHOXYPHENYL)-4-ARYL-3-HYDRAZINOCARBONYLMETHYLTHIO-4H-1,2,4-TRIAZOLES
    SINGH, SP
    CAMPBELL, RE
    STENBERG, VI
    PARMAR, SS
    SPECTROSCOPY LETTERS, 1980, 13 (04) : 217 - 226
  • [44] SYNTHESIS OF 5-(3,4,5-TRIMETHOXYPHENYL)-4-SUBSTITUTED ARYL-3-HYDRAZINOCARBONYLMETHYLTHIO-4H-1,2,4-TRIAZOLES AS POSSIBLE ANTI-INFLAMMATORY AGENTS
    JAISWAL, RK
    PARMAR, SS
    SINGH, SP
    BARTHWAL, JP
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1979, 16 (03) : 561 - 565
  • [45] 3-(4-bromophenyl)-5-(4-chlorophenyl)-1-phenyl-2-pyrazoline
    Guo, Huan-Mei
    Jian, Fang-Fang
    Xiao, Hai-Lian
    Sun, Xiao-Zheng
    Li, Yu-Feng
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 63 : o1435 - o1436
  • [46] 1-acetyl-3-(4-chlorophenyl)-5-(4-fluorophenyl)-2-pyrazoline
    Li, Jian
    Xiao, Huai-Fen
    Yang, Jie
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1391 - U1349
  • [47] 3-(4-chlorophenyl)-5-(4-methylphenyl)-1-phenyl-2-pyrazoline
    Guo, Huan-Mei
    Jian, Fang-Fang
    Zhao, Pu-Su
    Huang, Ben-Yu
    Lin, Cui-Hua
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 63 : O2622 - U1219
  • [48] 1-[3-(2-naphthyl)-5-(3,4,5-trimethoxyphenyl)4,5-dihydro-1H-pyrazol-1-yl]-ethanone
    Lu, Zhi-ke
    Diao, Hai-Lin
    Li, Shen
    He, Bin
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1638 - U3545
  • [49] 3-(4-chlorophenyl)-5-(4-fluorophenyl)-1-phenyl-2-pyrazoline
    Guo, Huan-Mei
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 63 : O3318 - U4436
  • [50] STRUCTURE OF DIMETHYL 2,3,4,5-TETRAHYDRO-2-OXO-5ALPHA-(3,4,5-TRIMETHOXYPHENYL)-3ALPHA,4BETA-FURANDICARBOXYLATE
    PETERSON, JR
    ROGERS, RD
    DO, HD
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1988, 44 : 1784 - 1786
12345