(±)-trans-2-[3-methoxy-4-(4-chlorophenyl thioethoxy)-5-cyanophenyl]-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran, a potent PAF-receptor antagonist

被引:2
|
作者
Ram, B [1 ]
Balram, B [1 ]
Prakash, PKS [1 ]
机构
[1] Osmania Univ, Dept Chem, Hyderabad 500007, Andhra Pradesh, India
关键词
platelet-activating factor; 2,5-transdiaryltetrahydrofuran; acetovanillone;
D O I
10.1016/S0040-4020(99)00544-X
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of (+/-)-trans-2-[3-methoxy-4-(chlorophenylthioethoxyphenyl)-5-cyanophenyl]-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran from conmercially available acetovanillone and 3,4,5-trimethoxybenzaldehyde is described. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:10163 / 10172
页数:10
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