Synthesis of chiral 1,3-diols by radical-mediated regioselective opening of 2,3-epoxy alcohols using cp2TiCl

被引：48
|
作者：
Chakraborty, TK [1 ]
Das, S [1 ]
机构：
[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India
来源：
TETRAHEDRON LETTERS | 2002年 / 43卷 / 12期
关键词：
epoxy alcohols; Katsuki-Sharpless reactions; epoxide opening; 1,3-diol;
D O I：
10.1016/S0040-4039(02)00241-1
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Radical-mediated opening of chiral 2,3-epoxy alcohols la-e, regioselectively at the 2-position, using cp(2)TiCl in the absence of a hydrogen source leads to the formation of the 1,3-diols 2a-e. (C) 2002 Published by Elsevier Science Ltd.
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页码：2313 / 2315
页数：3
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