Synthesis of chiral 1,3-diols by radical-mediated regioselective opening of 2,3-epoxy alcohols using cp2TiCl

被引：48

作者：

Chakraborty, TK ^{[1
]}

Das, S ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 12期

关键词：

epoxy alcohols; Katsuki-Sharpless reactions; epoxide opening; 1,3-diol;

D O I：

10.1016/S0040-4039(02)00241-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Radical-mediated opening of chiral 2,3-epoxy alcohols la-e, regioselectively at the 2-position, using cp(2)TiCl in the absence of a hydrogen source leads to the formation of the 1,3-diols 2a-e. (C) 2002 Published by Elsevier Science Ltd.

引用

页码：2313 / 2315

页数：3

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