A NEW SYNTHESIS OF 5-HYDROXY-2-ISOXAZOLINES AND THEIR CONVERSION INTO ISOXAZOLES

被引：0

作者：

MAREI, MG

GHONAIM, RA

机构：

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 1993年 / 32卷 / 04期

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中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of 1,5-diarylpent-1-yne-3,5-diones (1) or 2,6-diaryl-4H-pyran-4-ones (2) with hydroxylamine in ethanol leads to the formation of 5-hydroxyisoxazolines (3, 6) along with isoxazoles (7, 8) as minor products. The isoxazolines can be converted into isoxazoles on prolonged heating with xylene. The structure of the interadiate 5-hydroxyisoxazolines was established from their IR, UV, H-1 NMR and mass spectral data.

引用

页码：418 / 421

页数：4

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