3-Chloro-4-fluoro-N-{[3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methyl}aniline

被引：3
|
作者：
Bawa, Sandhya [1 ]
Ahmad, Fasih [1 ]
Kumar, Suresh [1 ]
机构：
[1] Jamia Hamdard, Fac Pharm, Dept Pharmaceut Chem, New Delhi 110062, India
来源：
MOLBANK | 2009年 / 04期
关键词：
reductive amination; pyrazolylamine; NaBH4/I-2;
D O I：
10.3390/M640
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A direct reductive amination of 3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde 2 with 3-chloro-4-flouroaniline using NaBH4/I-2 as a reducing agent is described. The reaction was carried out in MeOH under neutral conditions at room temperature to give the secondary amine, 3-chloro-4-fluoro-N-{[3-(4-methoxyphenyl)-1-phenyl-1-H-pyrazol-4-yl]methyl} aniline (3).
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页数：4
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