NEUTROPHIL CHEMOTACTIC FACTOR PRODUCED BY JAPANESE ENCEPHALITIS-VIRUS STIMULATED MACROPHAGES

被引：0
|
作者：
KHANNA, N [1 ]
AGNIHOTRI, M [1 ]
MATHUR, A [1 ]
CHATURVEDI, UC [1 ]
机构：
[1] KING GEORGE V MEM HOSP,POSTGRAD DEPT MICROBIOL,LUCKNOW 226003,UTTAR PRADESH,INDIA
来源：
CLINICAL AND EXPERIMENTAL IMMUNOLOGY | 1991年 / 86卷 / 02期
关键词：
JAPANESE ENCEPHALITIS VIRUS; NEUTROPHIL CHEMOTACTIC FACTOR; MACROPHAGE DERIVED CYTOKINE; NEUTROPHILIA;
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The mechanism of neutrophil leucocytosis in cases of Japanese encephalitis is not known, We here report that during Japanese encephalitis virus (JEV) infection in mice the splenic macrophages secrete a chemotactic factor that attracts the neutrophils. The peak activity of macrophage derived factor (MDF) was observed on day 7 following infection. The MDF acted in a dose-dependent manner. This chemoattractant was purified by low pressure liquid chromatography and gave a single band of 10 kD on silver stained polyacrylamide gel. The MDF was found to be heat resistant and sensitive to prolonged incubation with proteases.
引用
收藏
页码：299 / 303
页数：5
相关论文
共 50 条
  • [11] THE NATURAL-HISTORY OF JAPANESE ENCEPHALITIS-VIRUS
    ROSEN, L
    ANNUAL REVIEW OF MICROBIOLOGY, 1986, 40 : 395 - 414
  • [12] STUDIES ON NEGATIVE STAINING OF JAPANESE ENCEPHALITIS-VIRUS
    HAYASHI, K
    JOURNAL OF ELECTRON MICROSCOPY, 1972, 21 (02): : 156 - &
  • [13] FUNCTIONAL MAPPING OF THE JAPANESE ENCEPHALITIS-VIRUS GENOME
    MASON, PW
    MCADA, PC
    BURKE, DS
    DALRYMPLE, JM
    SCHMALJOHN, CS
    FOURNIER, MJ
    MASON, TL
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1986, : 282 - 282
  • [14] JAPANESE ENCEPHALITIS-VIRUS INFECTION DURING PREGNANCY
    MATHUR, A
    TANDON, HO
    MATHUR, KR
    SARKARI, NBS
    SINGH, UK
    CHATURVEDI, UC
    INDIAN JOURNAL OF MEDICAL RESEARCH, 1985, 81 (JAN) : 9 - 12
  • [15] CONGENITAL INFECTION OF MICE WITH JAPANESE ENCEPHALITIS-VIRUS
    MATHUR, A
    ARORA, KL
    CHATURVEDI, UC
    INFECTION AND IMMUNITY, 1981, 34 (01) : 26 - 29
  • [16] TRANSOVARIAL TRANSMISSION OF JAPANESE ENCEPHALITIS-VIRUS BY MOSQUITOS
    ROSEN, L
    TESH, RB
    LIEN, JC
    CROSS, JH
    SCIENCE, 1978, 199 (4331) : 909 - 911
  • [17] IMMUNE TYPING OF JAPANESE ENCEPHALITIS-VIRUS STRAINS
    BOCHKOVA, NG
    POGODINA, VV
    VOPROSY VIRUSOLOGII, 1980, (03) : 318 - 322
  • [18] EFFECT OF CURRENT JAPANESE ENCEPHALITIS VACCINE ON DIFFERENT STRAINS OF JAPANESE ENCEPHALITIS-VIRUS
    OKUNO, Y
    OKAMOTO, Y
    YAMADA, A
    BABA, K
    YABUUCHI, H
    VACCINE, 1987, 5 (02) : 128 - 132
  • [19] MONOCLONAL IMMUNOGLOBULINS TO JAPANESE ENCEPHALITIS-VIRUS ANTIGENS
    NOVOKHATSKY, AS
    MALAKHOVA, IV
    LOGINOVA, NV
    DERYABIN, PG
    LEBEDEVA, GA
    ALESHKIN, VA
    VOPROSY VIRUSOLOGII, 1986, (03) : 314 - 318
  • [20] SEQUENTIAL EVENTS IN THE MORPHOGENESIS OF JAPANESE ENCEPHALITIS-VIRUS
    LEARY, K
    BLAIR, CD
    JOURNAL OF ULTRASTRUCTURE RESEARCH, 1980, 72 (02): : 123 - 129
12345