NEW 1,2,6-THIADIAZINE DIOXIDE ACYCLONUCLEOSIDES - SYNTHESIS AND ANTIVIRAL EVALUATION

被引：14
|
作者：
ESTEBAN, AI
JUANES, O
CONDE, S
GOYA, P
DECLERCQ, E
MARTINEZ, A
机构：
[1] CSIC, INST QUIM MED, E-28006 MADRID, SPAIN
[2] KATHOLIEKE UNIV LEUVEN, REGA INST MED RES, B-3000 LOUVAIN, BELGIUM
来源：
BIOORGANIC & MEDICINAL CHEMISTRY | 1995年 / 3卷 / 11期
关键词：
D O I：
10.1016/0968-0896(95)00140-C
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
New acyclonucleosides derived from 1,2,6-thiadiazine dioxide systems have been synthesized. Lipase-mediated deacylation procedure was used to obtain the deprotected derivatives. All the newly prepared compounds were tested as antiviral agents, but none of them showed significant activity.
引用
收藏
页码：1527 / 1535
页数：9
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