Does the heart's hormone, ANP, help in congestive heart failure?

被引:0
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作者
Winaver, J
Hoffman, A
Abassi, Z
Haramati, A
机构
[1] TECHNION ISRAEL INST TECHNOL,FAC MED,RAMBAM MED CTR,DEPT SURG,IL-31096 HAIFA,ISRAEL
[2] GEORGETOWN UNIV,SCH MED,DEPT PHYSIOL & BIOPHYS,WASHINGTON,DC 20007
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中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
In congestive heart failure, increased secretion of atrial natriuretic peptide (ANP) is an important compensatory mechanism that unloads the failing heart and promotes renal salt and water excretion. However, activation of opposing sodium-retaining factors, particularly the renin-angiotensin system, reduces renal responsiveness to ANP and shifts the cardiovascular system to a state of decompensation.
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页码:247 / 253
页数:7
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