CYTOKINE-INDUCED AND PNEUMOCYSTIS-CARINII INDUCED L-ARGININE OXIDATION BY MURINE AND HUMAN PULMONARY ALVEOLAR MACROPHAGES

被引:0
|
作者
SHERMAN, MP [1 ]
LORO, ML [1 ]
WONG, VZ [1 ]
TASHKIN, DP [1 ]
机构
[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT MED,LOS ANGELES,CA 90024
来源
JOURNAL OF PROTOZOOLOGY | 1991年 / 38卷 / 06期
关键词
CITRULLINE; CYTOTOXICITY; INTERFERON GAMMA; LIPOPOLYSACCHARIDE; NITRATE; NITRITE;
D O I
暂无
中图分类号
Q95 [动物学];
学科分类号
071002 ;
摘要
Lipopolysaccharide plus interferon gamma stimulated the L-arginine-.NO pathway of murine, but not human pulmonary alveolar macrophages. Pneumocystis carinii induced .NO production by both murine and human pulmonary alveolar macrophages suggesting that the parasite stimulates L-arginine oxidation in these cells. The potential anti-Pneumocystis activity of .NO warrants further study.
引用
收藏
页码:S234 / S236
页数:3
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