CYTOKINE-INDUCED AND PNEUMOCYSTIS-CARINII INDUCED L-ARGININE OXIDATION BY MURINE AND HUMAN PULMONARY ALVEOLAR MACROPHAGES

被引：0

作者：

SHERMAN, MP ^{[1
]}

LORO, ML ^{[1
]}

WONG, VZ ^{[1
]}

TASHKIN, DP ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT MED,LOS ANGELES,CA 90024

来源：

JOURNAL OF PROTOZOOLOGY | 1991年 / 38卷 / 06期

关键词：

CITRULLINE; CYTOTOXICITY; INTERFERON GAMMA; LIPOPOLYSACCHARIDE; NITRATE; NITRITE;

D O I：

暂无

中图分类号：

Q95 [动物学];

学科分类号：

071002 ;

摘要：

Lipopolysaccharide plus interferon gamma stimulated the L-arginine-.NO pathway of murine, but not human pulmonary alveolar macrophages. Pneumocystis carinii induced .NO production by both murine and human pulmonary alveolar macrophages suggesting that the parasite stimulates L-arginine oxidation in these cells. The potential anti-Pneumocystis activity of .NO warrants further study.

引用

页码：S234 / S236

页数：3

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