[ASTERISK-C]OCTANOIC ACID BREATH TEST TO MEASURE GASTRIC-EMPTYING RATE OF SOLIDS

被引：49
|
作者：
MAES, BD
GHOOS, YF
RUTGEERTS, PJ
HIELE, MI
GEYPENS, B
VANTRAPPEN, G
机构：
[1] UNIV HOSP GASTHUISBERG,DEPT MED,DIV GASTROENTEROL,B-3000 LOUVAIN,BELGIUM
[2] UNIV HOSP GASTHUISBERG,GASTROINTESTINAL RES CTR,B-3000 LOUVAIN,BELGIUM
来源：
DIGESTIVE DISEASES AND SCIENCES | 1994年 / 39卷 / 12期
关键词：
GASTRIC EMPTYING; SOLIDS; BREATH TEST; OCTANOIC ACID;
D O I：
10.1007/BF02300385
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
We have developed a breath test to measure solid gastric emptying using a standardized scrambled egg test meal (250 kcal) labeled with [C-14]octanoic acid or [C-13]octanoic acid. In vitro incubation studies showed that octanoic acid is a reliable marker of the solid phase. The breath test was validated in 36 subjects by simultaneous radioscintigraphic and breath test measurements. Nine healthy volunteers were studied after intravenous administration of 200 mg erythromycin and peroral administration of 30 mg propantheline, respectively. Erythromycin significantly enhanced gastric emptying, while propantheline significantly reduced gastric emptying rates. We conclude that the [*C]octanoic breath test is a promising and reliable test for measuring the gastric emptying rate of solids.
引用
收藏
页码：S104 / S106
页数：3
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