HEPATOPROTECTIVE EFFECT OF SELENIUM AND VITAMIN-E IN RABBITS FED A HIGH-FAT DIET

被引:0
|
作者
WOJCICKI, J
BARCEWWISZNIOWSKA, B
KRASOWSKA, B
ROZEWICKA, L
SAMOCHOWIEC, L
机构
来源
FOLIA BIOLOGICA-KRAKOW | 1991年 / 39卷 / 1-4期
关键词
HIGH-FAT DIET; LIVER DAMAGE; SELENIUM; VITAMIN-E; RABBIT;
D O I
暂无
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The high-fat diet consisted of cholesterol, hydrogenated coconut oil, and cholic acid. In the blood serum and in liver homogenate lipid content, cholesterol, and triglycerides were assayed. Cytochrome P-450 concentration in liver microsomes was also estimated. In animals receiving selenium and vitamin E, the content of lipid fractions in the blood serum and liver homogenate fell, while the cytochrome P-450 content in the liver microsomes was markedly elevated. The intensified protective effect of vitamin E and selenium applied in combination against changes induced in the liver of animals receiving a HFD was confirmed by macroscopic and microscopic examination of the organ.
引用
收藏
页码:37 / 47
页数:11
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